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This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chondrocyte-derived ezrin-like protein; FERM, ARHGEF and pleckstrin domain-containing protein 1; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; PH domain-containing family C member 2; Pleckstrin homology domain-containing family C member 2; protein phosphatase 1, regulatory subunit 75
Gene Aliases: CDEP; FARP1; FARP1-IT1; PLEKHC2; PPP1R75
UniProt ID: (Human) Q9Y4F1
Entrez Gene ID: (Human) 10160
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