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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVAEESGPGA QNSPYQLRRK TLLPKRTACP TKNSMEGAST STTENFGHRA KRARVSGKSQ DLSAAPAEQY LQEKLPDEVV LKIFSYLLEQ DLCRAACVCK RFSELANDPI LWKRLYMEVF EYTRPMMHPE PGKFYQINPE EYEHPNPWKE SFQQLYKGAH VKPGFAEHFY SNPARYKGRE NMLYYDTIED ALGGVQEAHF DGLIFVHSGI YTDEWIYIES PITMIGAAPG KVADKVIIEN TRDSTFVFME GSEDAYVGYM TIRFNPDDKS AQHHNAHHCL EITVNCSPII DHCIIRSTCT VGSAVCVSGQ GACPTIKHCN ISDCENVGLY ITDHAQGIYE DNEISNNALA GIWVKNHGNP IIRRNHIHHG RDVGVFTFDH GMGYFESCNI HRNRIAGFEV KAYANPTVVR CEIHHGQTGG IYVHEKGRGQ FIENKIYANN FAGVWITSNS DPTIRGNSIF NGNQGGVYIF GDGRGLIEGN DIYGNALAGI QIRTNSCPIV RHNKIHDGQH GGIYVHEKGQ GVIEENEVYS NTLAGVWVTT GSTPVLRRNR IHSGKQVGVY FYDNGHGVLE DNDIYNHMYS GVQIRTGSNP KIRRNKIWGG QNGGILVYNS GLGCIEDNEI FDNAMAGVWI KTDSNPTLRR NKIHDGRDGG ICIFNGGRGL LEENDIFRNA QAGVLISTNS HPILRKNRIF DGFAAGIEIT NHATATLEGN QIFNNRFGGL FLASGVNVTM KDNKIMNNQD AIEKAVSRGQ CLYKISSYTS YPMHDFYRCH TCNTTDRNAI CVNCIKKCHQ GHDVEFIRHD RFFCDCGAGT LSNPCTLAGE PTHDTDTLYD SAPPIESNTL QHN
FBXO11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for FBXO11. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F-box only protein 11; FLJ12673; MGC44383; Protein arginine N-methyltransferase 9; ubiquitin protein ligase E3 component n-recognin 6; VIT-1; Vitiligo-associated protein 1; vitiligo-associated protein VIT-1
Gene Aliases: FBX11; FBXO11; PRMT9; UBR6; UG063H01; VIT1
UniProt ID: (Human) Q86XK2
Entrez Gene ID: (Human) 80204
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