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FBXO3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp564B092; F-box only protein 3; F-box protein FBA; F-box protein FBX3
Gene Aliases: 1200002G09Rik; 1700026K02Rik; AI046358; FBA; FBX3; FBXO3
UniProt ID: (Human) Q9UK99, (Mouse) Q9DC63
Entrez Gene ID: (Human) 26273, (Mouse) 57443
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