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Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
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Protein Aliases: DKFZp434B027; DKFZp434J1815; F-box only protein 14; F-box only protein 31; FLJ22477; MGC15419; MGC9527; putative breast cancer tumor-suppressor; SCF ubiquitin ligase specificity factor
Gene Aliases: 1110003O08Rik; 2310046N15Rik; FBX14; FBX31; FBXO14; FBXO31; MNCb-2609; MRT45; PP2386; RGD1561069
UniProt ID: (Human) Q5XUX0, (Rat) B2RYN2, (Mouse) Q3TQF0
Entrez Gene ID: (Human) 79791, (Rat) 498959, (Mouse) 76454
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