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Proteintech
FBXO32 Monoclonal Antibody (3C2G3)
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Product Details
67172-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3C2G3
Immunogen
FBXO32 Fusion Protein Ag25247
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: atrogin 1; Atrogin-1; atrophy gene 1; F-box only protein 32; fbxo25; FLJ32424; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein
Gene Aliases: 4833442G10Rik; AI430017; ATROGIN1; Fbx32; FBXO32; Gm20361; MAFbx
UniProt ID: (Human) Q969P5, (Pig) Q1A730, (Rat) Q91Z62, (Mouse) Q9CPU7
Entrez Gene ID: (Human) 114907, (Pig) 733657, (Rat) 171043, (Mouse) 67731
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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