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Invitrogen
FBXO45 Polyclonal Antibody
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FBXO45 Antibody (PA5-49458) in WB
Western blot analysis of FBXO45 in HT-1080 whole cell lysate. Samples were incubated with FBXO45 polyclonal antibody (Product # PA5-49458) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 31 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-49458
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 83-115 amino acids from human FBXO45.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2634912
Target Information
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: F-box only protein 45; F-box/SPRY domain-containing protein 1; hFbxo45
Gene Aliases: FBX45; FBXO45
UniProt ID: (Human) P0C2W1
Entrez Gene ID: (Human) 200933
neuron migration
cellular response to DNA damage stimulus
protein ubiquitination
cerebral cortex radially oriented cell migration
cerebral cortex tangential migration
corticospinal tract morphogenesis
anterior commissure morphogenesis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
synapse assembly involved in innervation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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