Proteintech

FBXO5 Polyclonal Antibody

FBXO5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 13

FBXO5 Antibody (10872-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human placenta tissue slide using 10872-1-AP ( FBXO5 Antibody) at dilution of 1:200 (under 40x lens).

Product Image Gallery

Product Details

10872-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FBXO5 Fusion Protein Ag1296 (1-447 aa encoded by BC018905)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSRRPCSCA LRPPRCSCSA SPSAVTAAGR PRPSDSCKEE SSTLSVKMKC DFNCNHVHSG LKLVKPDDIG RLVSYTPAYL EGSCKDCIKD YERLSCIGSP IVSPRIVELE TESKRLHNKE NQHVQQTLNS TNEIEALETS RLYEDSGYSS FSLQSGLSEH EEGSLLEENF GDSLQSCLLQ IQSPDQYPNK NLLPVLHFEK VVCSTLKKNA KRNPKVDREM LKEIIARGNF RLQNIIGRKM GLECVDILSE LFRRGLRHVL ATILAQLSDM DLINVSKVST TWKKILEDDK GAFQLYSKAI QRVTENNNKF SPHASTREYV MFRTPLASVQ KSAAQTSLKK DAQTKLSNQG DQKGSTYSRH NEFSEVAKTL KKNESLKACI RCNSPAKYDC YLQRATCKRE GCGFDYCTKC LCNYHTTKDC SDGKLLKASC KIGPLPGTKK SKKNLRRL (1-447 aa encoded by BC018905)

Target Information

F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Expression significance of Emi1, UBCH10 and CyclinB1 in esophageal squamous cell carcinoma.

Pathology oncology research : POR

Li H,Yang C,Chen K,Sun M

Fri Jun 02 00:00:00 UTC 2023

DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation.

Nature communications

Xu X,Chang CW,Li M,Omabe K,Le N,Chen YH,Liang F,Liu Y

Sat Mar 04 00:00:00 UTC 2023

Exploring the role of FBXO5 in gastric cancer.

Molecular and cellular probes

Zhang J,Zhang G,Wang K,Cui F,Yang H,Jiao Z

Thu Jun 01 00:00:00 UTC 2023

The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.

Experimental cell research

Wei P,Jiang J,Xiao M,Zeng M,Liu X,Zhao B,Chen F

Tue Mar 01 00:00:00 UTC 2022

CRL4^AMBRA1 is a master regulator of D-type cyclins.

Nature

Simoneschi D,Rona G,Zhou N,Jeong YT,Jiang S,Milletti G,Arbini AA,O'Sullivan A,Wang AA,Nithikasem S,Keegan S,Siu Y,Cianfanelli V,Maiani E,Nazio F,Cecconi F,Boccalatte F,Fenyö D,Jones DR,Busino L,Pagano M

Thu Apr 01 00:00:00 UTC 2021

An upstream open reading frame regulates vasculogenic mimicry of glioma via ZNRD1-AS1/miR-499a-5p/ELF1/EMI1 pathway.

Journal of cellular and molecular medicine

Wang M,Yang C,Liu X,Zheng J,Xue Y,Ruan X,Shen S,Wang D,Li Z,Cai H,Liu Y

Mon Jun 01 00:00:00 UTC 2020

Identification of aberrantly expressed F-box proteins in squamous-cell lung carcinoma.

Journal of cancer research and clinical oncology

Wang K,Qu X,Liu S,Yang X,Bie F,Wang Y,Huang C,Du J

Wed Aug 01 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: Early mitotic inhibitor 1; f-box only protein 31; F-box only protein 5; F-box protein Fbx5; fbxo5

View more View less

Gene Aliases: 2510044I10Rik; C85305; EMI1; FBX5; Fbxo31; FBXO5

View more View less

UniProt ID: (Human) Q9UKT4, (Mouse) Q7TSG3

View more View less

Entrez Gene ID: (Human) 26271, (Mouse) 67141, (Rat) 292263

View more View less

Function(s)

protein binding protein kinase binding metal ion binding zinc ion binding

Process(es)

oocyte maturation cell cycle spindle assembly involved in female meiosis I mitotic nuclear division regulation of mitotic cell cycle vesicle organization regulation of meiotic nuclear division negative regulation of meiotic nuclear division microtubule polymerization spindle assembly cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle positive regulation of meiosis I obsolete inhibition of APC-Cdc20 complex activity G1/S transition of mitotic cell cycle regulation of transcription involved in G1/S transition of mitotic cell cycle regulation of mitotic nuclear division positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

FBXO5 Polyclonal Antibody

FBXO5 Antibody (10872-1-AP) in IHC (P)

Product Details

10872-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Not applicable (N/A)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!