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Product Details
MA5-34738
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JG35-83
Immunogen
Recombinant protein within Human Emi1 aa 128-244
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848646
Product Specific Information
Positive Control: LOVO, Siha, Rat cerebellum tissue, human tonsil tissue, human colon cancer tissue, human kidney tissue, mouse cerebellum tissue.
Target Information
F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Early mitotic inhibitor 1; F-box only protein 5; F-box protein Fbx5
Gene Aliases: EMI1; FBX5; Fbxo31; FBXO5
UniProt ID: (Human) Q9UKT4
Entrez Gene ID: (Human) 26271
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
oocyte maturation
spindle assembly involved in female meiosis I
mitotic nuclear division
regulation of mitotic nuclear division
regulation of mitotic cell cycle
vesicle organization
negative regulation of meiotic nuclear division
microtubule polymerization
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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