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Proteintech
FBXW5 Polyclonal Antibody
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Product Details
18321-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBXW5 Fusion Protein Ag13163 (217-566 aa encoded by BC014297)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VLWLNNAFQ DVESENVNVV KRLFKIQNLN ASTVRTVMVA DCSRFDSPDL LLEAGDPATS PCRIFDLGSD NEEVVAGPAP AHAKEGLRHF LDRVLEGRAQ PQLSERMLET KVAELLAQGH TKPPERSATG AKSKYLIFTT GCLTYSPHQI GIKQILPHQM TTAGPVLGEG RGSDAFFDAL DHVIDIHGHI IGMGLSPDNR YLYVNSRAWP NGAVVADPMQ PPPIAEEIDL LVFDLKTMRE VRRALRAHRA YTPNDECFFI FLDVSRDFVA SGAEDRHGYI WDRHYNICLA RLRHEDVVNS VVFSPQEQEL LLTASDDATI KAWRSPRTMR VLQAPRPRPR TFFSWLASQR R (217-566 aa encoded by BC014297)
Target Information
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: F-box and WD-40 domain protein 5; F-box and WD-40 domain-containing protein 5; F-box protein Fbw5; F-box/WD repeat-containing protein 5; WD repeat-containing F-box protein FBW5
Gene Aliases: AI159739; FBW5; FBXW5; PP3971
UniProt ID: (Human) Q969U6, (Mouse) Q9QXW2, (Rat) Q4KLI9
Entrez Gene ID: (Human) 54461, (Mouse) 30839, (Rat) 362081
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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