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FCAR Antibody (PA5-121219) in WB
Western blot analysis of FCAR in extracts of 293T cells. Samples were incubated with FCAR Polyclonal antibody (Product # PA5-121219) followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Product Details
PA5-121219
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1).
Conjugate
Form
Liquid
Concentration
1.66 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914791
Product Specific Information
Positive test controls include: 293T. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein.
Immunogen sequence: LMIIKNSTYR EIGRRLKFWN ETDPEFVIDH MDANKAGRYQ CQYRIGHYRF RYSDTLELVV TGLYGKPFLS ADRGLVLMPG ENISLTCSSA HIPFDRFSLA KEGELSLPQH QSGEHPANFS LGPVDLNVSG IYRCYGWYNR SPYLWSFPSN ALELVVTDSI HQDYTTQNLI RMAVAGLVLV ALLAILVENW HSHTALNKEA SADVAEPSWS QQMCQPGLTF ARTPSVCK
Target Information
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; IgA Fc receptor; Immunoglobulin alpha Fc receptor
Gene Aliases: CD89; CTB-61M7.2; FcalphaRI; FCAR
UniProt ID: (Human) P24071
Entrez Gene ID: (Human) 2204
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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