Invitrogen

FCER1G Polyclonal Antibody

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View all (5) FCER1G antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Product Details

PA5-115222

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

Immunoprecipitation (IP)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human FCER1G(Accession P30273), corresponding to amino acid residues K52-Q86.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2899858

Product Specific Information

Antibody detects endogenous levels of total FCER1G.

Target Information

The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Fc epsilon receptor Ig; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; Fc receptor gamma-chain; Fc receptor, IgE, high affinity I, gamma polypeptide; Fc-epsilon RI-gamma; FceRI gamma; FcRgamma; gamma polypeptide; High affinity immunoglobulin epsilon receptor subunit gamma; IgE Fc receptor subunit gamma; immunoglobulin E receptor, high affinity, gamma chain

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Gene Aliases: AI573376; CD23; Fce1g; FcepsilonRI; FCER1G; FcR-gamma; FcR[g]; FCRG; FcRgamma; Ly-50

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UniProt ID: (Human) P30273, (Rat) P20411, (Mouse) P20491

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Entrez Gene ID: (Human) 2207, (Rat) 25441, (Mouse) 14127

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Function(s)
protein binding IgE receptor activity IgE binding IgG binding transmembrane signaling receptor activity
Process(es)
positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity positive regulation of type I hypersensitivity neutrophil activation involved in immune response Fc receptor mediated stimulatory signaling pathway serotonin secretion by platelet phagocytosis, engulfment signal transduction cell surface receptor signaling pathway integrin-mediated signaling pathway regulation of platelet activation immunoglobulin mediated immune response antigen processing and presentation of exogenous peptide antigen via MHC class II neutrophil chemotaxis positive regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of mast cell cytokine production negative regulation of mast cell apoptotic process Fc-epsilon receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium positive regulation of mast cell degranulation mast cell activation positive regulation of phagocytosis regulation of immune response positive regulation of immune response protein localization to plasma membrane T cell differentiation involved in immune response Fc-gamma receptor signaling pathway innate immune response stimulatory C-type lectin receptor signaling pathway blood coagulation platelet activation receptor internalization leukocyte migration cellular response to low-density lipoprotein particle stimulus
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