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Invitrogen
FCGR2B Recombinant Rabbit Monoclonal Antibody (HL1948)
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Product Details
MA5-47232
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1948
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human CD32B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938304
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIb; Fc gamma RIIb; Fc receptor, IgG, low affinity IIb; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; fc-gamma-RIIa; Fc-gamma-RIIb; FcGR; FCGR2A1; FcRII; fcRII-a; fcRII-b; FGFR2B; IgG Fc receptor II beta; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-b
Gene Aliases: CD32; CD32B; FCG2; FcgammaRIIB2; FCGR2; FCGR2B; FCRII; IGFR2
UniProt ID: (Human) P31994, (Rat) Q63203
Entrez Gene ID: (Human) 2213, (Rat) 289211
negative regulation of type I hypersensitivity
immune complex clearance
negative regulation of immunoglobulin production
negative regulation of inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of humoral immune response mediated by circulating immunoglobulin
receptor-mediated endocytosis
phagocytosis, engulfment
defense response
immune response
cell surface receptor signaling pathway
response to bacterium
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of B cell proliferation
response to estradiol
endocytic recycling
negative regulation of interleukin-10 production
negative regulation of neutrophil apoptotic process
mast cell activation
negative regulation of phagocytosis
positive regulation of phagocytosis
negative regulation of immune response
cellular response to molecule of bacterial origin
cellular response to lipopolysaccharide
signal transduction
viral process
regulation of immune response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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