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Invitrogen
FCHO2 Polyclonal Antibody
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Product Details
PA5-34390
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 15 amino acid synthetic peptide near the center of human FCHO2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551742
Product Specific Information
A suggested positive control is rat heart tissue lysate.
PA5-34390 can be used with blocking peptide PEP-1433.
Target Information
FCHO2 (FCH domain only 2) is a ubiquitously expressed member of the FCFBS superfamily characterized by FES-CIP4 homology (FCH) domain, an FBH domain, and an SH3 domain. Both FCHO2 and the related protein FCHO1 are mediators of clathrin-mediated endocytosis, acting to sculpt the initial bud site and recruit the clathrin machinery for clathrin-coated vesicle formation. FCHO2 binds to Eps15, an important adaptor protein in clathrin-mediated endocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: F-BAR domain only protein 2; FCH domain only protein 2
Gene Aliases: 5832424M12Rik; AA387320; FCHO2; RGD1565396
UniProt ID: (Human) Q0JRZ9, (Mouse) Q3UQN2
Entrez Gene ID: (Human) 115548, (Mouse) 218503, (Rat) 309129
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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