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Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: IRVQGASSS AAPPTLNPAP QKSAAPGTAP EEAPGPLPPP PTPSSEDPGF SSPLGMPDPH LYHQMGLLLK HMQDVRVLLG HLLMELRELS GHQKPGTTKA TAE (275-376 aa encoded by BC006521)
Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fc receptor homolog expressed in B cells (FREB); Fc receptor homolog expressed in B-cells; Fc receptor related protein X; Fc receptor-like A; Fc receptor-like and mucin-like 1; Fc receptor-like and mucin-like protein 1; Fc receptor-like protein; Fc receptor-related protein X; FcRX
Gene Aliases: FCRL; FCRL1; FCRLA; FCRLb; FCRLc1; FCRLc2; FCRLd; FCRLe; FCRLM1; FCRLX; FCRX; FREB; UNQ291/PRO329
UniProt ID: (Human) Q7L513
Entrez Gene ID: (Human) 84824
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