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Invitrogen
FES Polyclonal Antibody
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Product Details
PA5-51568
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FES. Recombinant protein control fragment (Product #RP-95943).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2641592
Product Specific Information
Immunogen sequence: DSAQAKRKYQ EASKDKDRDK AKDKYVRSLW KLFAHHNRYV LGVRAAQLHH QHHHQLLLPG LLRSLQDLHE EMACILKEIL QEYLEISSLV QDEVVAIHRE MAAAAARIQP EAEYQGFLRQ YGSAPDVPPC VTFDESLLEE GEPLEP
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.
Target Information
FES (FPS) is a tyrosine protein kinase that is required for maintenance of cellular transformation. Its chromosomal location is linked to a specific translocation event identified in patients with acute promyelocytic leukemia, and it is also involved in normal hematopoiesis. Alternative splicing results in multiple variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.7.10.2; feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog; feline sarcoma oncogene; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Oncogene FES, feline sarcoma virus; p93c-fes; Proto-oncogene c-Fes; Proto-oncogene c-Fps; proto-oncogene tyrosine-protein kinase Fes/Fps; Tyrosine-protein kinase Fes/Fps; Variant 4
Gene Aliases: FES; FPS
UniProt ID: (Human) P07332
Entrez Gene ID: (Human) 2242
microtubule bundle formation
protein phosphorylation
chemotaxis
epidermal growth factor receptor signaling pathway
multicellular organism development
cell proliferation
regulation of cell shape
positive regulation of neuron projection development
peptidyl-tyrosine phosphorylation
regulation of cell adhesion
positive regulation of microtubule polymerization
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
regulation of mast cell degranulation
innate immune response
regulation of cell differentiation
positive regulation of myeloid cell differentiation
protein autophosphorylation
centrosome organization
regulation of vesicle-mediated transport
regulation of cell motility
positive regulation of actin cytoskeleton reorganization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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