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Invitrogen
FEZ1 Polyclonal Antibody
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FEZ1 Antibody (PA5-90412) in WB
Western blot analysis of FEZ1 in extracts of various cell lines. Samples were incubated with FEZ1 Polyclonal antibody (Product # PA5-90412) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.
Product Details
PA5-90412
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human FEZ1 (NP_0050941)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806059
Product Specific Information
Immunogen sequence: MEAPLVSLDE EFEDLRPSCS EDPEEKPQCF YGSSPHHLED PSLSELENFS SEIISFKSME DLVNEFDEKL NVCFRNYNAK TENLAPVKNQ LQIQEEEETL QDEEVWDALT DNYIPSLSED WRDPNIEALN GNCSDTEIHE KEEEEFNEKS ENDSGINEEP; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane, Cytoplasm, centrosome, cytoskeleton, microtubule organizing center
Target Information
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: F37; Fasciculation and elongation protein zeta-1; protein kinase C-binding protein Zeta1; zygin 1; Zygin I; Zygin-1
Gene Aliases: Fez1; UNC-76; UNC76
UniProt ID: (Rat) P97577, (Mouse) Q8K0X8
Entrez Gene ID: (Rat) 81730, (Mouse) 235180
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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