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Product Details
H00152273-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FGD5 (AAH35364.1, 1 a.a. approximately 540 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRALDDMDHE GRDTLAREEL RQGLSELPAI HDLHQGILEE LEERLSNWES QQKVADVFLA REQGFDHHAT HILQFDRYLG LLSENCLHSP RLAAAVREFE QSVQGGSQTA KHRLLRVVQR LFQYQVLLTD YLNNLCPDSA EYDNTQGALS LISKVTDRAN DSMEQGENLQ KLVHIEHSVR GQGDLLQPGR EFLKEGTLMK VTGKNRRPRH LFLMNDVLLY TYPQKDGKYR LKNTLAVANM KVSRPVMEKV PYALKIETSE SCLMLSASSC AERDEWYGCL SRALPEDYKA QALAAFHHSV EIRERLGVSL GERPPTLVPV THVMMCMNCG CDFSLTLRRH HCHACGKIVC RNCSRNKYPL KYLKDRMAKV CDGCFGELKK RGRAVPGLMR ERPVSMSFPL SSPRFSGSAF SSVFQSINPS TFKKQKKVPS ALTEVAASGE GSAISGYLSR CKRGKRHWKK LWFVIKGKVL YTYMASEDKV ALESMPLLGF TIAPEKEEGS SEVGPIFHLY HKKTLFYSFK AEDTNSAQRW IEAMEDASVL
Target Information
FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FYVE, RhoGEF and PH domain-containing protein 5; Zinc finger FYVE domain-containing protein 23
Gene Aliases: FGD5; ZFYVE23
UniProt ID: (Human) Q6ZNL6
Entrez Gene ID: (Human) 152273
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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