Invitrogen

FGF-8A Recombinant Rabbit Monoclonal Antibody (HL2369)

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA5-50507

Applications
Tested Dilution
Publications

Immunohistochemistry (IHC)

1:100-1:500
-
Product Specifications

Species Reactivity

Zebrafish

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

HL2369

Immunogen

Recombinant fragment of zebrafish Fgf8a.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3092947

Target Information

FGF-8 is a heparin-binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8a, FGF-8b, FGF-8e and FGF-8f. The human and murine FGF-8a and FGF-8b are identical, unlike human and mouse FGF-8e and FGF-8f, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ace; acerebellar; cb110; etID309886.13; fb73a06; FGF-8; fgf8; Fibroblast growth factor 8; fibroblast growth factor 8 a; ibd5031; secreted protein

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Gene Aliases: ace; cb110; etID309886.13; fgf-8; fgf8; fgf8a; id:ibd5031; wu:fb73a06

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UniProt ID: (Zebrafish) O57341

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Entrez Gene ID: (Zebrafish) 30538

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Function(s)
fibroblast growth factor receptor binding growth factor activity
Process(es)
cell fate specification somitogenesis heart morphogenesis cardiac ventricle morphogenesis determination of left/right symmetry brain development peripheral nervous system development endoderm development mesoderm development fibroblast growth factor receptor signaling pathway embryonic pattern specification organ morphogenesis anterior/posterior pattern specification dorsal/ventral pattern formation cardioblast differentiation positive regulation of somitomeric trunk muscle development cerebellum development midbrain-hindbrain boundary morphogenesis rhombomere 5 development rhombomere 6 development cerebellum formation locus ceruleus development positive regulation of Wnt signaling pathway neuron differentiation positive regulation of cell migration thyroid gland development midbrain development hindbrain development notochord development otic vesicle formation midbrain-hindbrain boundary development embryonic camera-type eye development embryonic heart tube development negative regulation of endodermal cell fate specification otic placode formation regulation of bone remodeling determination of dorsal identity paraxial mesoderm development neuron fate specification embryonic neurocranium morphogenesis skeletal system morphogenesis oligodendrocyte differentiation inner ear development striated muscle cell differentiation cartilage development atrial cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation pharyngeal system development retina development in camera-type eye embryonic retina morphogenesis in camera-type eye cilium morphogenesis ectodermal placode formation somite development taste bud formation closure of optic fissure Kupffer's vesicle development otic vesicle development
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