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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FGF10 Antibodies

          Invitrogen

          FGF10 Polyclonal Antibody

          View all (11) FGF10 antibodies

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          Cite FGF10 Polyclonal Antibody

          • Antibody Testing Data (3)
          FGF10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FGF10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          FGF10 Antibody (PA5-81501) in IHC (P)

          Immunohistochemical staining of human FGF10 in human prostatic carcinoma with FGF10 Polyclonal Antibody (Product # PA5-81501, 1:1,000, formalin-fixed paraffin embedded sections). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FGF10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FGF10 Antibody in Western Blot (WB)
          FGF10 Antibody in Immunoprecipitation (IP)

          Product Details

          PA5-81501

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          - -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:500-1:2,000
          -

          Immunoprecipitation (IP)

          4-8 µL/mg of lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide corresponding to the C-terminus of the Human FGF10/KGF2
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A, Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2788708

          Product Specific Information

          This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

          This antibody has specificity for Human FGF10.

          Target Information

          FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FGF; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10; Keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria

          View more View less

          Gene Aliases: FGF10

          View more View less

          UniProt ID: (Human) O15520

          View more View less

          Entrez Gene ID: (Human) 2255

          View more View less

          Function(s)
          protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity fibroblast growth factor receptor binding type 2 fibroblast growth factor receptor binding protein binding growth factor activity heparin binding 1-phosphatidylinositol-3-kinase activity chemoattractant activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity
          Process(es)
          establishment of mitotic spindle orientation MAPK cascade activation of MAPK activity angiogenesis metanephros development organ induction mesonephros development blood vessel remodeling metanephros morphogenesis determination of left/right symmetry salivary gland development negative regulation of cell proliferation fibroblast growth factor receptor signaling pathway regulation of smoothened signaling pathway embryonic pattern specification epithelial cell migration positive regulation of epithelial cell migration positive regulation of keratinocyte proliferation regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation pituitary gland development embryonic genitalia morphogenesis thyroid gland development otic vesicle formation positive regulation of vascular endothelial growth factor receptor signaling pathway pancreas development hair follicle morphogenesis embryonic camera-type eye development actin cytoskeleton reorganization positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle response to estradiol response to lipopolysaccharide positive regulation of ATPase activity lacrimal gland development regulation of activin receptor signaling pathway protein localization to cell surface somatic stem cell population maintenance phosphatidylinositol-3-phosphate biosynthetic process wound healing tissue regeneration odontogenesis of dentin-containing tooth muscle cell fate commitment positive regulation of MAPK cascade positive regulation of GTPase activity keratinocyte proliferation negative regulation of cell differentiation positive regulation of DNA repair positive regulation of DNA replication positive regulation of Notch signaling pathway positive regulation of transcription, DNA-templated positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter positive regulation of Ras protein signal transduction phosphatidylinositol phosphorylation regulation of saliva secretion phosphatidylinositol-mediated signaling positive regulation of fibroblast proliferation spleen development thymus development embryonic digestive tract morphogenesis branching morphogenesis of an epithelial tube female genitalia morphogenesis male genitalia morphogenesis positive regulation of lymphocyte proliferation epithelial cell proliferation urothelial cell proliferation positive regulation of urothelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation white fat cell differentiation positive chemotaxis induction of positive chemotaxis smooth muscle cell differentiation positive regulation of keratinocyte migration radial glial cell differentiation positive regulation of epithelial cell proliferation involved in wound healing limb bud formation lung epithelium development lung saccule development bronchiole morphogenesis bud outgrowth involved in lung branching bud elongation involved in lung branching mesenchymal-epithelial cell signaling involved in lung development Type II pneumocyte differentiation prostatic bud formation fibroblast growth factor receptor signaling pathway involved in mammary gland specification mammary gland bud formation submandibular salivary gland formation epithelial cell proliferation involved in salivary gland morphogenesis regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling branch elongation involved in salivary gland morphogenesis semicircular canal fusion mesenchymal cell differentiation involved in lung development secretion by lung epithelial cell involved in lung growth lung proximal/distal axis specification tear secretion positive regulation of white fat cell proliferation ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade Harderian gland development negative regulation of cell cycle arrest positive regulation of hair follicle cell proliferation positive regulation of canonical Wnt signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
          It has to be done as per old AB suggested Products section.
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