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Proteintech
FGF13 Polyclonal Antibody
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Product Details
26235-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FGF13 Fusion Protein Ag23965 (212-245 aa encoded by BC034340)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LTEFSRSGS GTPTKSRSVS GVLNGGKSMS HNEST (212-245 aa encoded by BC034340)
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AFGF; ECGF; ECGFA; ECGFB; FGF; FGF 1; FGF alpha; FGF-13; FGF13A; FGFA; FHF-2; Fibroblast growth factor; Fibroblast growth factor 13; Fibroblast growth factor homologous factor 2; GLIO703; HBGF 1; HBGF1
Gene Aliases: FGF-13; FGF13; FGF2; FHF-2; FHF2
UniProt ID: (Human) Q92913, (Mouse) P70377
Entrez Gene ID: (Human) 2258, (Mouse) 14168
MAPK cascade
neuron migration
negative regulation of microtubule depolymerization
signal transduction
cell-cell signaling
nervous system development
learning
memory
hippocampus development
cerebral cortex cell migration
activation of protein kinase activity
establishment of neuroblast polarity
microtubule polymerization
negative regulation of collateral sprouting
protein localization to plasma membrane
apoptotic process
cell proliferation
positive regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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