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FGF5 Polyclonal Antibody

FGF5 Antibody in Immunocytochemistry (ICC/IF)

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FGF5 Antibody (18171-1-AP) in ICC/IF

Immunofluorescent analysis of NIH/3T3 cells using 18171-1-AP (FGF5 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

FGF5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FGF5 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

18171-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:20-1:200

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FGF5 Fusion Protein Ag12824 (16-268 aa encoded by BC074858)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: LSAWAHGEK RLAPKGQPGP AATDRNPRGS SSRQSSSSAM SSSSASSSPA ASLGSQGSGL EQSSFQWSPS GRRTGSLYCR VGIGFHLQIY PDGKVNGSHE ANMLSVLEIF AVSQGIVGIR GVFSNKFLAM SKKGKLHASA KFTDDCKFRE RFQENSYNTY ASAIHRTEKT GREWYVALNK RGKAKRGCSP RVKPQHISTH FLPRFKQSEQ PELSFTVTVP EKKKPPSPIK PKIPLSAPRK NTNSVKYRLK FRFG (16-268 aa encoded by BC074858)

Target Information

Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

The Lnc-RNA APPAT Suppresses Human Aortic Smooth Muscle Cell Proliferation and Migration by Interacting With MiR-647 and FGF5 in Atherosclerosis.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

Meng F,Han L,Liang Q,Lu S,Huang Y,Liu J

Fri Dec 01 00:00:00 UTC 2023

Commercial dishes with gelatin-free microstructured inserts for elongated stem cell self-renewal and pluripotency.

iScience

Ban Q,Hui W,Duan Q,Liu W,Zhang M,Li X,Kang H,Shi Z,Zhang Y,Hou J,Xu X,Ye S,Zhang B,Xu X

Fri Apr 21 00:00:00 UTC 2023

FGF5 protects heart from sepsis injury by attenuating cardiomyocyte pyroptosis through inhibiting CaMKII/NFκB signaling.

Biochemical and biophysical research communications

Cui S,Li Y,Zhang X,Wu B,Li M,Gao J,Xia H,Xu L

Sun Dec 25 00:00:00 UTC 2022

Genetic susceptibility analysis of FGF5 polymorphism to preeclampsia in Chinese Han population.

Molecular genetics and genomics : MGG

Xin Q,Han Y,Jiang W,Wang J,Luan Y,Ji Q,Sun W

Sun May 01 00:00:00 UTC 2022

Genetic susceptibility analysis of FGF5 polymorphism to preeclampsia in Chinese Han population.

Molecular genetics and genomics : MGG

Xin Q,Han Y,Jiang W,Wang J,Luan Y,Ji Q,Sun W

Sun May 01 00:00:00 UTC 2022

Genetic susceptibility analysis of FGF5 polymorphism to preeclampsia in Chinese Han population.

Molecular genetics and genomics : MGG

Xin Q,Han Y,Jiang W,Wang J,Luan Y,Ji Q,Sun W

Sun May 01 00:00:00 UTC 2022

Genetic susceptibility analysis of FGF5 polymorphism to preeclampsia in Chinese Han population.

Molecular genetics and genomics : MGG

Xin Q,Han Y,Jiang W,Wang J,Luan Y,Ji Q,Sun W

Sun May 01 00:00:00 UTC 2022

Fibroblast growth factor 5 overexpression ameliorated lipopolysaccharide-induced apoptosis of hepatocytes through regulation of the phosphoinositide-3-kinase/protein kinase B pathway.

Chinese medical journal

Cui S,Li Y,Zhang X,Wu B,Li M,Gao J,Xu L,Xia H

Mon Dec 05 00:00:00 UTC 2022

FGF5 alleviated acute lung injury via AKT signal pathway in endothelial cells.

Biochemical and biophysical research communications

Li Y,Cui S,Wu B,Gao J,Li M,Zhang F,Xia H

Sat Dec 17 00:00:00 UTC 2022

FGF5 alleviated acute lung injury via AKT signal pathway in endothelial cells.

Biochemical and biophysical research communications

Li Y,Cui S,Wu B,Gao J,Li M,Zhang F,Xia H

Sat Dec 17 00:00:00 UTC 2022

Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells.

Communications biology

Rore H,Owen N,Piña-Aguilar RE,Docherty K,Sekido R

Mon Jun 28 00:00:00 UTC 2021

Generation of VEGF knock-in Cashmere goat via the CRISPR/Cas9 system.

International journal of biological sciences

Hu X,Hao F,Li X,Xun Z,Gao Y,Ren B,Cang M,Liang H,Liu D

Fri Jan 21 00:00:00 UTC 2022

Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice.

Frontiers in pharmacology

Zhao J,Lin H,Wang L,Guo K,Jing R,Li X,Chen Y,Hu Z,Gao S,Xu N

Tue Jul 27 00:00:00 UTC 2021

Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice.

Frontiers in pharmacology

Zhao J,Lin H,Wang L,Guo K,Jing R,Li X,Chen Y,Hu Z,Gao S,Xu N

Tue Jul 27 00:00:00 UTC 2021

CRISPR Start-Loss: A Novel and Practical Alternative for Gene Silencing through Base-Editing-Induced Start Codon Mutations.

Molecular therapy. Nucleic acids

Chen S,Xie W,Liu Z,Shan H,Chen M,Song Y,Yu H,Lai L,Li Z

Fri Sep 04 00:00:00 UTC 2020

CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen.

Genes

Xu Y,Liu H,Pan H,Wang X,Zhang Y,Yao B,Li N,Lai L,Li Z

Wed Mar 11 00:00:00 UTC 2020

Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5.

Genetics and molecular research : GMR

Wang T,Zhang Y,Wang HD,Shen Y,Liu N,Cao J,Yu XJ,Dong CS,He XY

Thu Oct 29 00:00:00 UTC 2015

Alpaca fiber growth is mediated by microRNA let-7b via down-regulation of target gene FGF5.

Genetics and molecular research : GMR

Wang T,Zhang Y,Wang HD,Shen Y,Liu N,Cao J,Yu XJ,Dong CS,He XY

Thu Oct 29 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: FGF; FGF-5; Fibroblast growth factor; Fibroblast growth factor 5; HBGF-5; Heparin-binding growth factor 5; Smag-82

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Gene Aliases: angora; Fgf-5; FGF5; go; HBGF-5; Smag-82; TCMGLY

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UniProt ID: (Human) P12034, (Mouse) P15656

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Entrez Gene ID: (Human) 2250, (Mouse) 14176

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Function(s)

protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity fibroblast growth factor receptor binding growth factor activity 1-phosphatidylinositol-3-kinase activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity receptor binding

Process(es)

MAPK cascade cell-cell signaling nervous system development cell proliferation positive regulation of cell proliferation fibroblast growth factor receptor signaling pathway glial cell differentiation regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation signal transduction involved in regulation of gene expression phosphatidylinositol-3-phosphate biosynthetic process positive regulation of GTPase activity phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling positive regulation of cell division

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FGF5 Polyclonal Antibody

FGF5 Antibody (18171-1-AP) in ICC/IF

Product Details

18171-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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