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Product Details
MA1-24684
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
FG9-77
Immunogen
Recombinant mouse FGF-9.
Conjugate
Form
Liquid
Concentration
2.1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2102980
Product Specific Information
Recommended positive controls: recombinant human FGF-9.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: elbow knee synostosis; FGF; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; Glia-activating factor; HBGF-9; Heparin-binding growth factor 9; M-FGF-9
Gene Aliases: Eks; FGF-9; FGF9; GAF; HBFG-9; HBGF-9; SYNS3
UniProt ID: (Human) P31371, (Mouse) P54130
Entrez Gene ID: (Human) 2254, (Mouse) 14180
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
osteoblast differentiation
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
cardiac left ventricle morphogenesis
cardiac ventricle development
protein import into nucleus
cell-cell signaling
multicellular organism development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
male gonad development
positive regulation of gene expression
cell differentiation
negative regulation of Wnt signaling pathway
male sex determination
lung development
embryonic limb morphogenesis
positive regulation of vascular endothelial growth factor receptor signaling pathway
positive regulation of activin receptor signaling pathway
inner ear morphogenesis
positive regulation of MAPK cascade
positive regulation of smoothened signaling pathway
positive regulation of transcription, DNA-templated
regulation of timing of cell differentiation
embryonic digestive tract development
embryonic skeletal system development
positive regulation of epithelial cell proliferation
positive regulation of cell division
positive regulation of cardiac muscle cell proliferation
lung-associated mesenchyme development
vasculogenesis involved in coronary vascular morphogenesis
positive regulation of canonical Wnt signaling pathway
MAPK cascade
eye development
signal transduction
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
substantia nigra development
phosphatidylinositol-3-phosphate biosynthetic process
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
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