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Invitrogen
FGFBP1 Polyclonal Antibody
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Product Details
PA5-77220
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human FGFBP1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2720947
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
FGFBP1 encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 17 kDa HBGF-binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-binding protein 1; FGF-BP; FGF-BP1; FGFBP-1; Fibroblast growth factor-binding protein 1; growth factor binding protein-1; growth factor-binding protein 1; heparin-binding growth factor binding protein
Gene Aliases: FGF-BP; FGF-BP1; FGFBP; FGFBP-1; FGFBP1; HBP17
UniProt ID: (Human) Q14512, (Mouse) O70514, (Rat) Q9QY10
Entrez Gene ID: (Human) 9982, (Mouse) 14181, (Rat) 64535
positive regulation of defense response to virus by host
cell-cell signaling
positive regulation of cell proliferation
positive regulation of fibroblast growth factor receptor signaling pathway
mitophagy in response to mitochondrial depolarization
signal transduction
negative regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
xenophagy
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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