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Invitrogen
FGFBP3 Polyclonal Antibody
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FIGURE: 1 / 5
FGFBP3 Antibody (PA5-103412) in ICC/IF
Immunocytochemistry analysis of FGFBP3 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with FGFBP3 polyclonal antibody (Product # PA5-103412) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-103412
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FGFBP3(Accession Q8TAT2), corresponding to amino acid residues E201-F251.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852755
Product Specific Information
Antibody detects endogenous levels of total FGFBP3.
Target Information
FGFBP3 is a heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF-binding protein 3; FGF-BP3; FGFBP-3; Fibroblast growth factor-binding protein 3
Gene Aliases: C10orf13; FGF-BP3; FGFBP3; PSEC0101
UniProt ID: (Human) Q8TAT2
Entrez Gene ID: (Human) 143282
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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