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Invitrogen
FGFR1OP Recombinant Rabbit Monoclonal Antibody (JE64-24)
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FIGURE: 1 / 7
FGFR1OP Antibody (MA5-44761) in IHC (P)
Immunohistochemistry analysis of FGFR1 Oncogene Partner in paraffin-embedded mouse lymph nodes tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with FGFR1 Oncogene Partner Monoclonal antibody (Product # MA5-44761) using a di... View More
Product Details
MA5-44761
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JE64-24
Immunogen
Synthetic peptide within human FGFR1 Oncogene Partner aa 350-399/399.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2931219
Target Information
This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Centrosomal protein 43; FGFR1 oncogene partner; fibroblast growth factor receptor 1 oncogene partner
Gene Aliases: 4930553O10Rik; CEP43; FGFR1OP; FOP
UniProt ID: (Human) O95684, (Mouse) Q66JX5, (Rat) Q4V7C1
Entrez Gene ID: (Human) 11116, (Mouse) 75296, (Rat) 683722
G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
positive regulation of cell proliferation
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
positive regulation of cell migration
microtubule anchoring
negative regulation of protein tyrosine kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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