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Abnova
FLCN Polyclonal Antibody, MaxPab™
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Product Details
H00201163-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FLCN (NP_653207.1, 1 a.a. approximately 342 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNAIVALCHF CELHGPRTLF CTEVLHAPLP QGDGNEDSPG QGEQAEEEEG GIQMNSRMRA HSPAEGASVE SSSPGPKKSD MCEGCRSLAA GHPGYISHDK ETSIKYVSHQ HPSHPQLFSI VRQACVRSLS CEVCPGREGP IFFGDEQHGF VFSHTFFIKD SLARGFQRWY SIITIMMDRI YLINSWPFLL GKVRGIIDEL QGKALKVFEA EQFGCPQRAQ RMNTAFTPFL HQRNGNAARS LTSLTSDDNL WACLHTSFAW LLKACGSRLT EKLLEGAPTE DTLVQMEKLA GEAGVLLPGP WPGWPWGGTS CLLSWQESLR EGNAALNQPR TSLREAHPPI SV
Target Information
This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein; Folliculin
Gene Aliases: BHD; FLCL; FLCN
UniProt ID: (Human) Q8NFG4
Entrez Gene ID: (Human) 201163
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
regulation of protein phosphorylation
positive regulation of protein phosphorylation
cell-cell junction assembly
positive regulation of autophagy
negative regulation of gene expression
negative regulation of mitochondrion organization
hemopoiesis
negative regulation of cell growth
negative regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
TOR signaling
regulation of TOR signaling
negative regulation of TOR signaling
positive regulation of TOR signaling
regulation of cytokinesis
negative regulation of Rho protein signal transduction
regulation of histone acetylation
positive regulation of apoptotic process
positive regulation of GTPase activity
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
negative regulation of protein kinase B signaling
negative regulation of ERK1 and ERK2 cascade
negative regulation of protein localization to nucleus
negative regulation of cell proliferation involved in kidney development
negative regulation of energy homeostasis
regulation of pro-B cell differentiation
negative regulation of ATP biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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