Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
H00147872-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FLJ32658 (AAH29811, 1 a.a. approximately 562 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDLPEGPVGG PTAEMYLRER PEEARLGMPV SLEEQILNST FEACDPQRTG TVAVAQVLAY LEAVTGQGPQ DARLQTLANS LDPNGEGPKA TVDLDTFLVV MRDWIAACQL HGGLELEEET AFQGALTSQQ LPSGCPEAEE PANLESFGGE DPRPELQATA DLLSSLEDLE LSNRRLVGEN AKLQRSMETA EEGSARLGEE ILALRKQLHS TQQALQFAKA MDEELEDLKT LARSLEEQNR SLLAQARQAE KEQQHLVAEM ETLQEENGKL LAERDGVKKR SQELAMEKDT LKRQLFECEH LICQRDTILS ERTRDVESLA QTLEEYRVTT QELRLEISRL EEQLSQTYEG PDELPEGAQL RRVGWTELLP PSLGLEIEAI RQKQEVATAD LSNPLCGVWQ WEEVIHETSE ETEFPSEAPA GGQRNFQGEP AHPEEGRKEP SMWLTRREEE EDAESQVTAD LPVPLGAPRP GDIPENPPER PARRELQQAL VPVMKKLVPV RRRAWGQLCL PPQRLRVTRH PLIPAPVLGL LLLLLLSVLL LGPSPPPTWP HLQLCYLQPP PV
Target Information
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Required for telomere attachment to nuclear envelope in the prophase of meiosis and for rapid telomere prophase movements implicating a SUN1/2:KASH5 LINC complex in which SUN1 and SUN2 seem to act at least partial redundantly. Required for homolog pairing during meiotic prophase in spermatocytes and probably oocytes. Essential for male and female gametogenesis. Recruits cytoplasmic dynein to telomere attachment sites at the nuclear envelope in spermatocytes. In oocytes is involved in meiotic resumption and spindle formation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 155; KASH domain-containing protein 5; Protein KASH5
Gene Aliases: CCDC155; KASH5
UniProt ID: (Human) Q8N6L0
Entrez Gene ID: (Human) 147872
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support