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FLRG Antibody (PA5-47106) in Neu
Neutralization of FLRG in K562 human chronic myelogenous leukemia cell line. Samples were incubated in FLRG polyclonal antibody (Product # PA5-47106). Recombinant Mouse Follistatin-related Gene Protein/FLRG inhibits Recombinant Human/Mouse/Rat Activin A induced hemoglobin expression in the K562 human chronic myelogenous leukemia cell line in a dose-dependent manner (orange line), as measured by the psuedoperoxidase assay. Inhibition of Recombinant Human/Mouse/Rat Activin A (7.5 ng/mL) activity elicited by Recombinant Mouse Follistatin-rela... View More
Product Details
PA5-47106
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Follistatin-related Gene Protein/FLRG Val24-Val256
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2605569
Product Specific Information
In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human FLRG is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Follistatin-like 3 is a secreted glycoprotein of the follistatin-module-protein family. It may have a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLRGFSRP; Follistatin-like protein 3; Follistatin-related gene protein; Follistatin-related protein 3
Gene Aliases: E030038F23Rik; Flrg; Fstl3
UniProt ID: (Mouse) Q9EQC7
Entrez Gene ID: (Mouse) 83554
ossification
hematopoietic progenitor cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of cell-cell adhesion
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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