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Alomone Labs, LTD
FLRT3 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 5
FLRT3 (extracellular) Antibody (AFR-053-200UL) in IHC (F)
Expression of FLRT3 in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-FLRT3 (extracellular) Antibody (#AFR-053), (1:200), followed by goat Anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal dentate gyrus region, showed immunoreactivity (green) in the granule layer (G) and in the hilus (H, arrows). B. Pre-incubation of the Antibody with FLRT3 ... View More
Product Details
AFR-053-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
((C)KQPDIKNPKLTKDQR, corresponding to amino acid residues 387-401 of rat FLRT3, Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signaling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fibronectin leucine rich transmembrane protein 3; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; Leucine-rich repeat transmembrane protein FLRT3
Gene Aliases: 5530600M07Rik; C430047I10Rik; FLRT3; HH21; KIAA1469; mKIAA1469; RGD1566005; UNQ856/PRO1865
UniProt ID: (Human) Q9NZU0, (Mouse) Q8BGT1, (Rat) B1H234
Entrez Gene ID: (Human) 23767, (Mouse) 71436, (Rat) 366205
axon guidance
negative chemotaxis
positive regulation of synapse assembly
cell adhesion
proepicardium cell migration involved in pericardium morphogenesis
negative regulation of protein kinase activity
synapse assembly
heart development
fibroblast growth factor receptor signaling pathway
cytokine-mediated signaling pathway
neuron projection development
negative regulation of JAK-STAT cascade
embryonic morphogenesis
response to axon injury
head development
cell-cell adhesion
neuron projection extension
Performance Guarantee
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