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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FMNL1 Antibodies

          Proteintech

          FMNL1 Polyclonal Antibody

          5 References
          View all (12) FMNL1 antibodies

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          Datasheet
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          Datasheet
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          Cite FMNL1 Polyclonal Antibody

          • Antibody Testing Data (7)
          FMNL1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          FMNL1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          FMNL1 Antibody (27834-1-AP) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using (Product # 27834-1-AP) (FMNL1 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FMNL1 Antibody in Immunocytochemistry (ICC/IF)
          FMNL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FMNL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FMNL1 Antibody in Western Blot (WB)
          FMNL1 Antibody in Western Blot (WB)
          FMNL1 Antibody in Western Blot (WB)
          FMNL1 Antibody in Western Blot (WB)

          Product Details

          27834-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:10,000
          View 2 publications 2 publications

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          FMNL1 Fusion Protein Ag27312 (357-501 aa encoded by BC111564)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          27834-1-AP is a rabbit polyclonal antibody recognizes the 125-150 kDa protein.

          Immunogen sequence: LYLERLRLT ESDKLQVQIQ AYLDNIFDVG ALLEDTETKN AVLEHMEELQ EQVALLTERL RDAENESMAK IAELEKQLSQ ARKELETLRE RFSESTAMGP SRRPPEPEKA PPAAPTRPSA LELKVEELEE KGLIRILRGP GDAVSI (357-501 aa encoded by B C111564)

          Target Information

          The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; Leukocyte formin

          View more View less

          Gene Aliases: C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; FRL1; KW-13

          View more View less

          UniProt ID: (Human) O95466

          View more View less

          Entrez Gene ID: (Human) 752

          View more View less

          Function(s)
          molecular_function protein binding profilin binding GTPase activating protein binding Rac GTPase binding actin filament binding
          Process(es)
          substrate-dependent cell migration regulation of cell shape cortical actin cytoskeleton organization actin filament severing
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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