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Invitrogen
FMNL1 Polyclonal Antibody
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FIGURE: 1 / 1
FMNL1 Antibody (PA5-88912) in WB
Western blot analysis of FMNL1 in extracts of various cell lines. Samples were incubated with FMNL1 Polyclonal antibody (Product # PA5-88912) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-88912
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_0058832)
Conjugate
Form
Liquid
Concentration
2.78 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805214
Product Specific Information
Immunogen sequence: DLHFLDKAGS VSLDSVLADV RSLQRGLELT QREFVRQDDC MVLKEFLRAN SPTMDKLLAD SKTAQEAFES VVEYFGENPK TTSPGLFFSL FSRFIKAYKK AEQEVEQWKK EAAAQEAGAD TPGKGEPPAP KSPPKARRPQ MDLISELKRR QQKEPLIYES DRDGAIEDII T; Positive Samples: LO2, A-549, Mouse brain; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Lipid-anchor, bleb, cell cortex, phagosome
Target Information
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; formin-related gene in leukocytes; Formin-related protein; Leukocyte formin; lymphocyte specific formin related protein
Gene Aliases: 8030453N10Rik; AI553564; C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; Fnrl; Frl; FRL1; Frls; KW-13
UniProt ID: (Human) O95466, (Mouse) Q9JL26
Entrez Gene ID: (Human) 752, (Mouse) 57778
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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