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FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. Itis suspectedbe involved in gastric cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Formin homology 2 domain-containing protein 3; formin-like 3; formin-like 3 protein; Formin-like protein 3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3
Gene Aliases: 2700073B04Rik; FBP11; FHOD3; FMNL3; FRL2; KIAA2014; mKIAA2014; WBP-3; WBP3
UniProt ID: (Human) Q8IVF7, (Mouse) Q6ZPF4
Entrez Gene ID: (Rhesus monkey) 712659, (Human) 91010, (Dog) 486555, (Mouse) 22379, (Rat) 300225
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