Proteintech

FMO3 Polyclonal Antibody

FMO3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

FMO3 Antibody (17469-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using (Product # 17469-1-AP) (FMO3 antibody) at dilution of 1:200 (under 10x lens).

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Product Details

17469-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FMO3 Fusion Protein Ag11405 (27-351 aa encoded by BC032016)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.16 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to FMO3.

Immunogen sequence: EPTCFEKSN DIGGLWKFSD HAEEGRASIY KSVFSNSSKE MMCFPDFPFP DDFPNFMHNS KIQEYIIAFA KEKNLLKYIQ FKTFVSSVNK HPDFATTGQW DVTTERDGKK ESAVFDAVMV CSGHHVYPNL PKESFPGLNH FKGKCFHSRD YKEPGVFNGK RVLVVGLGNS GCDIATELSR TAEQVMISSR SGSWVMSRVW DNGYPWDMLL VTRFGTFLKN NLPTAISDWL YMKQMNARFK HENYGLMPLN GVLRKEPVFN DELPASILCG IVSVKPNVKE FTETSAIFED GTIFEGIDCV IFATGYSFAY PFLDESIIKS RNNEII (27-351 aa encoded by BC032016)

Target Information

The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Effects of black raspberry extract on gut microbiota, microbial metabolites, and expressions of the genes involved in cholesterol and bile acid metabolisms in rats fed excessive choline with a high-fat diet.

Food science and biotechnology

Lim T,Lee K,Kim RH,Ryu J,Cha KH,Park SY,Koo SY,Hwang KT

Wed Mar 01 00:00:00 UTC 2023

Dietary titanium dioxide particles (E171) promote diet-induced atherosclerosis through reprogramming gut microbiota-mediated choline metabolism in APOE^-/- mice.

Journal of hazardous materials

Zhu X,Zhao L,Wang Y,Hu X,Zhu Y,Yang X

Mon Aug 15 00:00:00 UTC 2022

Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis.

EBioMedicine

Luo Y,Zhang Y,Han X,Yuan Y,Zhou Y,Gao Y,Yu H,Zhang J,Shi Y,Duan Y,Zhao X,Yan S,Hao H,Dai C,Zhao S,Shi J,Li W,Zhang S,Xu W,Fang N,Gong Y,Li Y

Mon Aug 01 00:00:00 UTC 2022

Berberine Improves Vascular Dysfunction by Inhibiting Trimethylamine-N-oxide via Regulating the Gut Microbiota in Angiotensin II-Induced Hypertensive Mice.

Frontiers in microbiology

Wang Z,Wu F,Zhou Q,Qiu Y,Zhang J,Tu Q,Zhou Z,Shao Y,Xu S,Wang Y,Tao J

Fri Apr 01 00:00:00 UTC 2022

Bioinformatics

Protein Aliases: Dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; Flavin-containing monooxygenase 3; FMO 3; FMO form 2; FMO II; Hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; Trimethylamine monooxygenase

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Gene Aliases: AW111792; dJ127D3.1; FMO3; FMOII; TMAU

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UniProt ID: (Human) P31513, (Rat) Q9EQ76, (Mouse) P97501

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Entrez Gene ID: (Human) 2328, (Rat) 84493, (Mouse) 14262

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Function(s)

monooxygenase activity N,N-dimethylaniline monooxygenase activity amino acid binding trimethylamine monooxygenase activity flavin adenine dinucleotide binding NADP binding oxidoreductase activity

Process(es)

xenobiotic metabolic process drug metabolic process oxidation-reduction process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FMO3 Polyclonal Antibody

FMO3 Antibody (17469-1-AP) in IHC (P)

Product Details

17469-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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