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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FMO3 Antibodies

          Invitrogen

          FMO3 Polyclonal Antibody

          1 Reference
          View all (19) FMO3 antibodies
          Datasheet
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          Datasheet
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          Cite FMO3 Polyclonal Antibody

          • Antibody Testing Data (3)
          FMO3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          FMO3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          FMO3 Antibody (PA5-27916) in IHC (P)

          FMO3 Polyclonal Antibody detects FMO3 protein at cytosol on human normal liver by immunohistochemical analysis. Sample: Paraffin-embedded normal liver. FMO3 Polyclonal Antibody (Product # PA5-27916) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FMO3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FMO3 Antibody in Western Blot (WB)
          FMO3 Antibody in Western Blot (WB)

          Product Details

          PA5-27916

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human FMO3. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2545392

          Product Specific Information

          Recommended positive controls: A549, H1299, Mouse liver.

          Predicted reactivity: Mouse (81%), Rat (83%), Dog (85%), Rabbit (84%), Rhesus Monkey (93%), Chimpanzee (100%), Bovine (82%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; Flavin-containing monooxygenase 3; FMO 3; FMO form 2; FMO II; Hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; Trimethylamine monooxygenase

          View more View less

          Gene Aliases: AW111792; dJ127D3.1; FMO3; FMOII; TMAU

          View more View less

          UniProt ID: (Human) P31513, (Mouse) P97501

          View more View less

          Entrez Gene ID: (Human) 2328, (Mouse) 14262

          View more View less

          Function(s)
          monooxygenase activity N,N-dimethylaniline monooxygenase activity amino acid binding trimethylamine monooxygenase activity flavin adenine dinucleotide binding NADP binding oxidoreductase activity
          Process(es)
          xenobiotic metabolic process drug metabolic process oxidation-reduction process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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