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Invitrogen
FMRP Monoclonal Antibody (6A15)
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Product Details
MA1-5771
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6A15
Immunogen
His-dFMR1 fusion protein (Drosophila melanogaster) (C-terminal 580aa) (aa 580-684).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2105561
Product Specific Information
MA1-5771 detects FMR1 in drosophila samples (does not cross react with human). Western blot detects a band of approximately 85kDa (predicted molecular weight: 82kDa).
Target Information
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CG6203-PA; CG6203-PB; CG6203-PC; CG6203-PD; CG6203-PE; CG6203-PF; CG6203-PG; CG6203-PH; CG6203-PI; CG6203-PJ; CG6203-PK; dFMR; dFmr1; drosophila fragile X mental retardation protein; Fmr1; Fmr1-PA; Fmr1-PB; Fmr1-PC; Fmr1-PD; Fmr1-PE; Fmr1-PF; Fmr1-PG; Fmr1-PH; Fmr1-PI; Fmr1-PJ; Fmr1-PK; FMRP; fragile X; fragile X mental retardation; fragile X mental retardation 1; fragile X mental retardation gene; fragile X mental retardation protein; fragile X mental retardation protein 1; Fragile X messenger ribonucleoprotein 1 homolog; fragile X protein; fragile x related; fragile X related protein; fragile X-related; fragile-X; Fragile-X mental retardation protein; Fragile-X-related; MGC87458
Gene Aliases: AT24755; BcDNA:GM08679; CG6203; dFMR; dFMR1; dFMRP; dFXR; dFXR1; dFXRP; Dmel\CG6203; Dmel_CG6203; dmfr1; EP(3)3517; FMR; FMR1; FMRP; FXR
UniProt ID: (Fruit fly) Q9NFU0
Entrez Gene ID: (Fruit fly) 37528
positive regulation of neuroblast proliferation
regulation of translation
chemotaxis
chemical synaptic transmission
neurotransmitter secretion
pole cell formation
germ cell development
sperm axoneme assembly
germarium-derived oocyte fate determination
oocyte dorsal/ventral axis specification
cellularization
axonogenesis
axon guidance
axonal fasciculation
synapse assembly
brain development
neuromuscular junction development
short-term memory
long-term memory
circadian rhythm
male courtship behavior
larval locomotory behavior
olfactory learning
regulation of synaptic growth at neuromuscular junction
regulation of mitotic cell cycle, embryonic
mushroom body development
negative regulation of translation
heterochromatin assembly
locomotion
regulation of cell proliferation
phototaxis
positive regulation of programmed cell death
mitotic cell cycle, embryonic
locomotor rhythm
negative regulation of imaginal disc growth
negative regulation of synaptic growth at neuromuscular junction
negative regulation of insulin receptor signaling pathway
habituation
germ-line cyst formation
neuron projection morphogenesis
dendrite morphogenesis
regulation of dendrite morphogenesis
negative regulation of dendrite morphogenesis
circadian sleep/wake cycle, sleep
regulation of synapse organization
synapse organization
detection of mechanical stimulus involved in sensory perception of touch
mRNA transport
regulation of synapse structural plasticity
negative regulation of synapse assembly
synaptic vesicle budding
medium-term memory
regulation of olfactory learning
synaptic vesicle clustering
regulation of neuromuscular synaptic transmission
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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