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Recommended positive controls: H1299, NIH-3T3, JC, BCL-1, PC-12.
Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: formin binding protein 17; Formin-binding protein 1; Formin-binding protein 17; hFBP17; MGC126804; Rapostlin
Gene Aliases: 1110057E06Rik; 2210010H06Rik; FBP1; FBP17; FNBP1; KIAA0554
UniProt ID: (Human) Q96RU3, (Rat) Q8R511, (Mouse) Q3UPI7
Entrez Gene ID: (Human) 23048, (Rat) 192348, (Mouse) 14269
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