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          • Primary Antibodies ›
          • PRPF40A Antibodies

          Bioss

          FNBP3 Polyclonal Antibody

          View all (8) PRPF40A antibodies

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          Cite FNBP3 Polyclonal Antibody

          • Antibody Testing Data (1)
          FNBP3 Antibody in Western Blot (WB)
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          FNBP3 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          FNBP3 Antibody (BS-13190R) in WB

          Lane 1: Siha cell lysates probed with FNBP3 Polyclonal Antibody, Unconjugated (bs-13190R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FNBP3 Antibody in Western Blot (WB)

          Product Details

          BS-13190R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human FNBP3, amino acids 851-957.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Fas ligand-associated factor 1; Fas-ligand associated factor 1; FBP-11; FLJ20585; formin binding protein 11; formin binding protein 3; Formin-binding protein 11; Formin-binding protein 3; HIP-10; Huntingtin yeast partner A; Huntingtin-interacting protein 10; Huntingtin-interacting protein A; NY-REN-6 antigen; pre-mRNA processing factor 40 homolog A; Pre-mRNA-processing factor 40 homolog A; PRP40 pre-mRNA processing factor 40 homolog A; Renal carcinoma antigen NY-REN-6

          View more View less

          Gene Aliases: 2810012K09Rik; FBP-11; FBP11; FLAF1; Fnbp11; FNBP3; HIP-10; HIP10; HSPC225; HYPA; NY-REN-6; Prp40; PRPF40A

          View more View less

          UniProt ID: (Human) O75400, (Mouse) Q8BRW4

          View more View less

          Entrez Gene ID: (Human) 55660, (Rat) 295607, (Mouse) 56194

          View more View less

          Function(s)
          RNA binding protein binding poly(A) RNA binding proline-rich region binding
          Process(es)
          cytoskeleton organization regulation of cell shape cell migration regulation of cytokinesis mRNA splicing, via spliceosome cell cycle cell division mRNA processing RNA splicing
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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