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          • Primary Antibodies ›
          • FOLR2 Antibodies

          Invitrogen

          FOLR2 Monoclonal Antibody (1905CT501.41.76)

          View all (22) FOLR2 antibodies
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          Cite FOLR2 Monoclonal Antibody (1905CT501.41.76)

          • Antibody Testing Data (1)
          FOLR2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          FOLR2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          FOLR2 Antibody (MA5-37763) in WB

          Western Blot analysis of FOLR2 using the FOLR2 Monoclonal Antibody (Product # MA5-37763) at a 1:1000-1:2000 dilution. Lane 1: Human spleen lysate, Lane 2: Human placenta lysate. Lysates/proteins were loaded at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size : 29 kDa. Blocking/Dilution buffer: 5% NFDM/TBST. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FOLR2 Antibody in Western Blot (WB)

          Product Details

          MA5-37763

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:2,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG2b, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1905CT501.41.76

          Immunogen

          recombiant protein from human FOLR2

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4

          Contains

          0.09% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2897687

          Target Information

          FOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FBP; Folate receptor 2; folate receptor 2 (fetal); Folate receptor beta; folate receptor, beta; Folate receptor, fetal/placental; folate-binding protein, fetal/placental; FR-beta; Placental folate-binding protein

          View more View less

          Gene Aliases: BETA-HFR; FBP; FBP/PL-1; FOLR2; FR-BETA; FR-P3

          View more View less

          UniProt ID: (Human) P14207

          View more View less

          Entrez Gene ID: (Human) 2350

          View more View less

          Function(s)
          folic acid binding drug binding folic acid transporter activity methotrexate binding folic acid receptor activity
          Process(es)
          monocyte chemotaxis receptor-mediated endocytosis inflammatory response positive regulation of cell proliferation folic acid transport regulation of thymidylate synthase biosynthetic process cellular response to folic acid
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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