Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Bioss
FOXB1 + FOXB2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
BS-11556R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human FOXB1 + FOXB2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: forkhead box B1a; forkhead box B1b; Forkhead box protein B1; Forkhead box protein B2; forkhead homolog 4; mesoderm/mesenchyme forkhead 3; Transcription factor FKH-4; Transcription factor FKH-5
Gene Aliases: bA159H20.4; C43; Fkh4; FKH5; FOXB1; Foxb1a; Foxb1b; FOXB2; Hfh-e5.1; HFKH-5; Mf3; Twh
UniProt ID: (Human) Q99853, (Human) Q5VYV0, (Mouse) Q64732, (Mouse) Q64733
Entrez Gene ID: (Human) 27023, (Human) 442425, (Rat) 367106, (Mouse) 64290, (Mouse) 14240, (Rat) 691398
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
somitogenesis
transcription from RNA polymerase II promoter
axon target recognition
lactation
visual learning
mammillary body development
hypothalamus cell migration
telencephalon cell migration
midbrain development
floor plate development
negative regulation of neuron apoptotic process
epithelial cell differentiation involved in mammary gland alveolus development
mammillothalamic axonal tract development
mammary gland lobule development
inferior colliculus development
cell migration in diencephalon
regulation of transcription, DNA-templated
anatomical structure morphogenesis
cell differentiation
urogenital system development
spinal cord development
thalamus development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support