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Invitrogen
FOXN4 Polyclonal Antibody
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Product Details
PA5-113857
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C terminal region of human FOXN4 (aa 362-411).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2884372
Product Specific Information
Immunogen sequence: HHQVQPQAHL APDSPAPAQT PPLHALPDLS PSPLPHPAMG RAPVDFINIS
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Zebrafish: 79%
Target Information
Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Forkhead box protein N4; forkhead/winged helix transcription factor FOXN4; sli; slipjig
Gene Aliases: FOXN4
UniProt ID: (Human) Q96NZ1
Entrez Gene ID: (Human) 121643
heart looping
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of heart contraction
retina layer formation
amacrine cell differentiation
atrioventricular canal development
positive regulation of transcription, DNA-templated
ventral spinal cord interneuron fate commitment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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