Proteintech

FOXO6 Polyclonal Antibody

FOXO6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FOXO6 Antibody (19122-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 19122-1-AP (FOXO6 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

FOXO6 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

19122-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

ChIP assay (ChIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

FOXO6 is a transcriptional activator.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

FOXO6 transcription inhibition of CTRP3 promotes OGD/R-triggered cardiac microvascular endothelial barrier disruption via SIRT1/Nrf2 signalling.

Folia morphologica

Zheng S,Wang Y,Guo W,Tan H

Wed Apr 03 00:00:00 UTC 2024

SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.

Cell death & disease

Cheng L,He Q,Liu B,Chen L,Lv F,Li X,Li Y,Liu C,Song Y,Xing Y

Tue Jan 31 00:00:00 UTC 2023

FOXO signaling pathway participates in oxidative stress-induced histone deacetylation.

Free radical research

Zuo M,Tong R,He X,Liu Y,Liu J,Liu S,Liu Y,Cao J,Ma L

Sun Jan 01 00:00:00 UTC 2023

PLOD3 contributes to HER-2 therapy resistance in gastric cancer through FoxO3/Survivin pathway.

Cell death discovery

Chen Y,Ye B,Wang C,Nie Y,Qin J,Shen Z

Thu Jul 14 00:00:00 UTC 2022

Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.

Aging cell

Dang R,Yang M,Cui C,Wang C,Zhang W,Geng C,Han W,Jiang P

Fri Oct 01 00:00:00 UTC 2021

Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m⁶A-GPR161 signalling axis.

RNA biology

Zong X,Wang H,Xiao X,Zhang Y,Hu Y,Wang F,Wang Y,Lu Z

Thu Apr 01 00:00:00 UTC 2021

Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m⁶A-GPR161 signalling axis.

RNA biology

Zong X,Wang H,Xiao X,Zhang Y,Hu Y,Wang F,Wang Y,Lu Z

Thu Apr 01 00:00:00 UTC 2021

Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m⁶A-GPR161 signalling axis.

RNA biology

Zong X,Wang H,Xiao X,Zhang Y,Hu Y,Wang F,Wang Y,Lu Z

Thu Apr 01 00:00:00 UTC 2021

Role and mechanism underlying FoxO6 in skeletal muscle in vitro and in vivo.

International journal of molecular medicine

Zhang L,Zhang Y,Zhou M,Wang S,Li T,Hu Z,Jin C

Thu Jul 01 00:00:00 UTC 2021

Involvement of the FOXO6 transcriptional factor in breast carcinogenesis.

Oncotarget

Lallemand F,Petitalot A,Vacher S,de Koning L,Taouis K,Lopez BS,Zinn-Justin S,Dalla-Venezia N,Chemlali W,Schnitzler A,Lidereau R,Bieche I,Caputo SM

Fri Jan 26 00:00:00 UTC 2018

Involvement of the FOXO6 transcriptional factor in breast carcinogenesis.

Oncotarget

Lallemand F,Petitalot A,Vacher S,de Koning L,Taouis K,Lopez BS,Zinn-Justin S,Dalla-Venezia N,Chemlali W,Schnitzler A,Lidereau R,Bieche I,Caputo SM

Fri Jan 26 00:00:00 UTC 2018

Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner.

Molecular and cellular biology

Ikeda M,Toyoshima F

Wed Mar 01 00:00:00 UTC 2017

Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner.

Molecular and cellular biology

Ikeda M,Toyoshima F

Wed Mar 01 00:00:00 UTC 2017

Elevated FOXO6 expression correlates with progression and prognosis in gastric cancer.

Oncotarget

Wang JH,Tang HS,Li XS,Zhang XL,Yang XZ,Zeng LS,Ruan Q,Huang YH,Liu GJ,Wang J,Cui SZ

Tue May 09 00:00:00 UTC 2017

Elevated FOXO6 expression correlates with progression and prognosis in gastric cancer.

Oncotarget

Wang JH,Tang HS,Li XS,Zhang XL,Yang XZ,Zeng LS,Ruan Q,Huang YH,Liu GJ,Wang J,Cui SZ

Tue May 09 00:00:00 UTC 2017

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.

eLife

Rothenberg SM,Concannon K,Cullen S,Boulay G,Turke AB,Faber AC,Lockerman EL,Rivera MN,Engelman JA,Maheswaran S,Haber DA

Mon Feb 16 00:00:00 UTC 2015

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.

eLife

Rothenberg SM,Concannon K,Cullen S,Boulay G,Turke AB,Faber AC,Lockerman EL,Rivera MN,Engelman JA,Maheswaran S,Haber DA

Mon Feb 16 00:00:00 UTC 2015

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.

eLife

Rothenberg SM,Concannon K,Cullen S,Boulay G,Turke AB,Faber AC,Lockerman EL,Rivera MN,Engelman JA,Maheswaran S,Haber DA

Mon Feb 16 00:00:00 UTC 2015

Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.

eLife

Rothenberg SM,Concannon K,Cullen S,Boulay G,Turke AB,Faber AC,Lockerman EL,Rivera MN,Engelman JA,Maheswaran S,Haber DA

Mon Feb 16 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: forkhead box O6; Forkhead box protein O6

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Gene Aliases: Foxo6

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UniProt ID: (Mouse) Q70KY4

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Entrez Gene ID: (Human) 100132074, (Rat) 313558, (Mouse) 329934

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Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding

Process(es)

regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter transcription, DNA-templated positive regulation of dendritic spine development regulation of transcription, DNA-templated anatomical structure morphogenesis cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FOXO6 Polyclonal Antibody

FOXO6 Antibody (19122-1-AP) in IHC (P)

Product Details

19122-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

Bioinformatics

Performance Guarantee

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