Product References
Preventive effects of Mycobacterium tuberculosis DNA vaccines on the mouse model with latent tuberculosis infection.
Frontiers in immunology
Liang Y,Li X,Yang Y,Xiao L,Liang Y,Mi J,Xue Y,Gong W,Wang L,Wang J,Zhang J,Shi Y,Peng B,Chen X,Zhao W,Wu X
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Fri Mar 03 00:00:00 UTC 2023
AHR/TET2/NT5E axis downregulation is associated with the risk of systemic lupus erythematosus and its progression.
Immunology
Cheng HH,Hung-Ke L,Sheu ML,Lee CY,Tsai YC,Lai DW
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2023
Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.
Frontiers in oncology
Babl N,Hofbauer J,Matos C,Voll F,Menevse AN,Rechenmacher M,Mair R,Beckhove P,Herr W,Siska PJ,Renner K,Kreutz M,Schnell A
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue Feb 14 00:00:00 UTC 2023
In chronic lymphocytic leukemia, activation of the thrombopoietin receptor promotes T-cell inhibitory properties, contributing to immunosuppression.
European journal of haematology
Ringelstein-Harlev S,Fanadka M,Horowitz NA,Bettman NP,Katz T
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2023
Pre-vaccination frequency of circulatory Tfh is associated with robust immune response to TV003 dengue vaccine.
PLoS pathogens
Izmirly AM,Pelletier AN,Connors J,Taramangalam B,Alturki SO,Gordon EA,Alturki SO,Mell JC,Swaminathan G,Karthik V,Kutzler MA,Kallas EG,Sekaly RP,Haddad EK
53-4776-42 was used in Flow Cytometry to provide novel insights into the favorable cTfh related immune status that persists in Dengue virus sero-positive individuals that correlate with their ability to mount robust vaccine specific immune responses.
Sat Jan 01 00:00:00 UTC 2022
FABP4 facilitates inflammasome activation to induce the Treg/Th17 imbalance in preeclampsia via forming a positive feedback with IL-17A.
Molecular therapy. Nucleic acids
Chang GP,Yang XL,Liu W,Lin S,Yang SL,Zhao MY
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Fri Jun 04 00:00:00 UTC 2021
VX-765 reduces neuroinflammation after spinal cord injury in mice.
Neural regeneration research
Chen J,Chen YQ,Shi YJ,Ding SQ,Shen L,Wang R,Wang QY,Zha C,Ding H,Hu JG,Lü HZ
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Wed Sep 01 00:00:00 UTC 2021
Soluble fibrinogen‑like protein 2 levels are decreased in patients with ischemic heart failure and associated with cardiac function.
Molecular medicine reports
You Y,Huang S,Liu H,Fan C,Liu K,Wang Z
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sun Aug 01 00:00:00 UTC 2021
Imbalance between T helper 1 and regulatory T cells plays a detrimental role in experimental Parkinson's disease in mice.
The Journal of international medical research
Li W,Luo Y,Xu H,Ma Q,Yao Q
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Heliyon
Singh Y,Trautwein C,Fendel R,Krickeberg N,Berezhnoy G,Bissinger R,Ossowski S,Salker MS,Casadei N,Riess O
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue Jun 01 00:00:00 UTC 2021
Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease.
NPJ Parkinson's disease
Thome AD,Atassi F,Wang J,Faridar A,Zhao W,Thonhoff JR,Beers DR,Lai EC,Appel SH
53-4776-42 was used in Flow Cytometry to document a shift towards a pro-inflammatory peripheral immune response in patients with Parkinson's disease (PD).
Thu May 13 00:00:00 UTC 2021
Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease.
NPJ Parkinson's disease
Thome AD,Atassi F,Wang J,Faridar A,Zhao W,Thonhoff JR,Beers DR,Lai EC,Appel SH
53-4776-42 was used in Flow Cytometry to document a shift towards a pro-inflammatory peripheral immune response in patients with Parkinson's disease (PD).
Thu May 13 00:00:00 UTC 2021
Unmasking the immune microecology of ductal carcinoma in situ with deep learning.
NPJ breast cancer
Narayanan PL,Raza SEA,Hall AH,Marks JR,King L,West RB,Hernandez L,Guppy N,Dowsett M,Gusterson B,Maley C,Hwang ES,Yuan Y
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Mon Mar 01 00:00:00 UTC 2021
Metabolic Disturbance and Th17/Treg Imbalance Are Associated With Progression of Gingivitis.
Frontiers in immunology
Wang W,Wang X,Lu S,Lv H,Zhao T,Xie G,Du Y,Fan Y,Xu L
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Wed Oct 20 00:00:00 UTC 2021
A follicular regulatory Innate Lymphoid Cell population impairs interactions between germinal center Tfh and B cells.
Communications biology
O'Connor MH,Muir R,Chakhtoura M,Fang M,Moysi E,Moir S,Carey AJ,Terk A,Nichols CN,Metcalf T,Petrovas C,Cameron MJ,Tardif V,Haddad EK
53-4776-42 was used in Flow cytometry/Cell sorting to investigate the role of follicular regulatory innate lymphoid cells in cancer.
Wed May 12 00:00:00 UTC 2021
Viable bacterial colonization is highly limited in the human intestine in utero.
Nature medicine
Rackaityte E,Halkias J,Fukui EM,Mendoza VF,Hayzelden C,Crawford ED,Fujimura KE,Burt TD,Lynch SV
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Single-Cell Analysis Reveals Fibroblast Clusters Linked to Immunotherapy Resistance in Cancer.
Cancer discovery
Kieffer Y,Hocine HR,Gentric G,Pelon F,Bernard C,Bourachot B,Lameiras S,Albergante L,Bonneau C,Guyard A,Tarte K,Zinovyev A,Baulande S,Zalcman G,Vincent-Salomon A,Mechta-Grigoriou F
53-4776 was used in Flow cytometry/Cell sorting to provide a significant advance in characterizing and understanding FAP+ CAF in cancer.
Tue Sep 01 00:00:00 UTC 2020
A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.
Nature immunology
Harb H,Stephen-Victor E,Crestani E,Benamar M,Massoud A,Cui Y,Charbonnier LM,Arbag S,Baris S,Cunnigham A,Leyva-Castillo JM,Geha RS,Mousavi AJ,Guennewig B,Schmitz-Abe K,Sioutas C,Phipatanakul W,Chatila TA
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Sep 28 00:00:00 UTC 2020
Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer.
Cell reports. Medicine
Li S,Simoni Y,Becht E,Loh CY,Li N,Lachance D,Koo SL,Lim TP,Tan EKW,Mathew R,Nguyen A,Golovato J,Berkson JD,Prlic M,Lee B,Minot SS,Nagarajan N,Dey N,Tan DSW,Tan IB,Newell EW
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue Jun 23 00:00:00 UTC 2020
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis.
JCI insight
Henderson LA,Hoyt KJ,Lee PY,Rao DA,Jonsson AH,Nguyen JP,Rutherford K,Julé AM,Charbonnier LM,Case S,Chang MH,Cohen EM,Dedeoglu F,Fuhlbrigge RC,Halyabar O,Hazen MM,Janssen E,Kim S,Lo J,Lo MS,Meidan E,Son MBF,Sundel RP,Stoll ML,Nusbaum C,Lederer JA,Chatila TA,Nigrovic PA
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Thu Mar 26 00:00:00 UTC 2020
Role of Vitamins A and D in BCR-ABL Arf-/- Acute Lymphoblastic Leukemia.
Scientific reports
Annu K,Cline C,Yasuda K,Ganguly S,Pesch A,Cooper B,Janke L,Payton M,Mukherjee K,Surman SL,Hurwitz JL,Schuetz EG
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue Feb 11 00:00:00 UTC 2020
T-Lymphocyte Subset Distribution and Activity in Patients With Glaucoma.
Investigative ophthalmology & visual science
Yang X,Zeng Q,Göktas E,Gopal K,Al-Aswad L,Blumberg DM,Cioffi GA,Liebmann JM,Tezel G
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2019
Can levamisole upregulate the equine cell-mediated macrophage (M1) dendritic cell (DC1) T-helper 1 (CD4 Th1) T-cytotoxic (CD8) immune response in vitro?
Journal of veterinary internal medicine
Witonsky S,Buechner-Maxwell V,Santonastasto A,Pleasant R,Werre S,Wagner B,Ellison S,Lindsay D
53-4776 was used in Flow cytometry/Cell sorting to study the effects and mechanism of action of levamisole in horses.
Fri Mar 01 00:00:00 UTC 2019
Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells.
Frontiers in immunology
Bell L,Lenhart A,Rosenwald A,Monoranu CM,Berberich-Siebelt F
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunofluorescence
Thu Oct 22 00:00:00 UTC 2020
Double negative T cells mediate Lag3-dependent antigen-specific protection in allergic asthma.
Nature communications
Tian D,Yang L,Wang S,Zhu Y,Shi W,Zhang C,Jin H,Tian Y,Xu H,Sun G,Liu K,Zhang Z,Zhang D
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Wed Sep 18 00:00:00 UTC 2019
HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy.
Oncoimmunology
Triulzi T,Forte L,Regondi V,Di Modica M,Ghirelli C,Carcangiu ML,Sfondrini L,Balsari A,Tagliabue E
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Tue Jan 12 00:00:00 UTC 2021
Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells.
JCI insight
Dawson NA,Lamarche C,Hoeppli RE,Bergqvist P,Fung VC,McIver E,Huang Q,Gillies J,Speck M,Orban PC,Bush JW,Mojibian M,Levings MK
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Thu Mar 21 00:00:00 UTC 2019
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Cancer cell
Arce Vargas F,Furness AJS,Litchfield K,Joshi K,Rosenthal R,Ghorani E,Solomon I,Lesko MH,Ruef N,Roddie C,Henry JY,Spain L,Ben Aissa A,Georgiou A,Wong YNS,Smith M,Strauss D,Hayes A,Nicol D,O'Brien T,Mårtensson L,Ljungars A,Teige I,Frendéus B,Pule M,Marafioti T,Gore M,Larkin J,Turajlic S,Swanton C,Peggs KS,Quezada SA
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Apr 09 00:00:00 UTC 2018
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer.
Cancer cell
Costa A,Kieffer Y,Scholer-Dahirel A,Pelon F,Bourachot B,Cardon M,Sirven P,Magagna I,Fuhrmann L,Bernard C,Bonneau C,Kondratova M,Kuperstein I,Zinovyev A,Givel AM,Parrini MC,Soumelis V,Vincent-Salomon A,Mechta-Grigoriou F
53-4776 was used in Flow cytometry/Cell sorting to study the role of carcinoma associated fibroblasts in the tumour microenvironment.
Mon Mar 12 00:00:00 UTC 2018
Analysis of immunobiologic markers in primary and recurrent glioblastoma.
Journal of neuro-oncology
Rahman M,Kresak J,Yang C,Huang J,Hiser W,Kubilis P,Mitchell D
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Sun Apr 01 00:00:00 UTC 2018
Effect of TGF-β1 on blood CD4+CD25high regulatory T cell proliferation and Foxp3 expression during non-small cell lung cancer blood metastasis.
Experimental and therapeutic medicine
Hu Y,Qi W,Sun L,Zhou H,Zhou B,Yang Z
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Wed Aug 01 00:00:00 UTC 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Wed Jan 31 00:00:00 UTC 2018
Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer.
Cell research
Su S,Liao J,Liu J,Huang D,He C,Chen F,Yang L,Wu W,Chen J,Lin L,Zeng Y,Ouyang N,Cui X,Yao H,Su F,Huang JD,Lieberman J,Liu Q,Song E
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2017
Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1.
Journal of virology
Miller SM,Miles B,Guo K,Folkvord J,Meditz AL,McCarter MD,Levy DN,MaWhinney S,Santiago ML,Connick E
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Fri Sep 01 00:00:00 UTC 2017
Alteration of Th17 and Foxp3+ regulatory T cells in patients with unexplained recurrent spontaneous abortion before and after the therapy of hCG combined with immunoglobulin.
Experimental and therapeutic medicine
Sha J,Liu F,Zhai J,Liu X,Zhang Q,Zhang B
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue Aug 01 00:00:00 UTC 2017
Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters.
BMC cancer
McDonnell AM,Cook A,Robinson BWS,Lake RA,Nowak AK
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Thu Jun 15 00:00:00 UTC 2017
HDAC inhibition potentiates immunotherapy in triple negative breast cancer.
Oncotarget
Terranova-Barberio M,Thomas S,Ali N,Pawlowska N,Park J,Krings G,Rosenblum MD,Budillon A,Munster PN
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue Dec 26 00:00:00 UTC 2017
Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics.
Scientific reports
Raijmakers RPH,Sprenkeler EGG,Aleva FE,Jacobs CWM,Kanneganti TD,Joosten LAB,van de Veerdonk FL,Gresnigt MS
53-4776 was used in Flow cytometry/Cell sorting to suggest a role for regulatory T-cells with a pro-inflammatory TH17-like phenotype in Aspergillus-associated immunopathology, and identifies key players, i.e. TLR2 and CTLA4, involved in this mechanism.
Wed Sep 13 00:00:00 UTC 2017
Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Cell
Clever D,Roychoudhuri R,Constantinides MG,Askenase MH,Sukumar M,Klebanoff CA,Eil RL,Hickman HD,Yu Z,Pan JH,Palmer DC,Phan AT,Goulding J,Gattinoni L,Goldrath AW,Belkaid Y,Restifo NP
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Thu Aug 25 00:00:00 UTC 2016
Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells--possible implications for the ICOS/ICOS-ligand axis in disease course and resolution.
Clinical and experimental immunology
Sakthivel P,Grunewald J,Eklund A,Bruder D,Wahlström J
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2016
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
Journal of immunology (Baltimore, Md. : 1950)
Younis RH,Han KL,Webb TJ
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2016
Development of Type 2, But Not Type 1, Leprosy Reactions is Associated with a Severe Reduction of Circulating and In situ Regulatory T-Cells.
The American journal of tropical medicine and hygiene
Vieira AP,Trindade MÂ,Pagliari C,Avancini J,Sakai-Valente NY,Duarte AJ,Benard G
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Fri Apr 01 00:00:00 UTC 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Wed Jun 01 00:00:00 UTC 2016
Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants.
Nature immunology
De Rosa V,Galgani M,Porcellini A,Colamatteo A,Santopaolo M,Zuchegna C,Romano A,De Simone S,Procaccini C,La Rocca C,Carrieri PB,Maniscalco GT,Salvetti M,Buscarinu MC,Franzese A,Mozzillo E,La Cava A,Matarese G
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2015
Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants.
Nature immunology
De Rosa V,Galgani M,Porcellini A,Colamatteo A,Santopaolo M,Zuchegna C,Romano A,De Simone S,Procaccini C,La Rocca C,Carrieri PB,Maniscalco GT,Salvetti M,Buscarinu MC,Franzese A,Mozzillo E,La Cava A,Matarese G
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2015
DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.
Human molecular genetics
Volk T,Pannicke U,Reisli I,Bulashevska A,Ritter J,Björkman A,Schäffer AA,Fliegauf M,Sayar EH,Salzer U,Fisch P,Pfeifer D,Di Virgilio M,Cao H,Yang F,Zimmermann K,Keles S,Caliskaner Z,Güner SÜ,Schindler D,Hammarström L,Rizzi M,Hummel M,Pan-Hammarström Q,Schwarz K,Grimbacher B
53-4776 was used in Flow cytometry/Cell sorting to investigate the range of phenotypes associated with DCLRE1C (ARTEMIS) mutations in humans.
Sun Dec 20 00:00:00 UTC 2015
Vitamin D deficiency contributes to the reduction and impaired function of naïve CD45RA⁺ regulatory T cell in chronic heart failure.
Journal of immunology research
Ma YH,Zhou YL,Yue CY,Zhang GH,Deng L,Xie GH,Xu WP,Shen LS
53-4776 was used in Flow cytometry/Cell sorting to investigate the impact of vitamin D supplementation on naïve Tregs.
Tue Jan 26 00:00:00 UTC 2016
Distinct patterns of intratumoral immune cell infiltrates in patients with HPV-associated compared to non-virally induced head and neck squamous cell carcinoma.
Oncoimmunology
Partlová S,Bouček J,Kloudová K,Lukešová E,Zábrodský M,Grega M,Fučíková J,Truxová I,Tachezy R,Špíšek R,Fialová A
53-4776 was used in Flow cytometry/Cell sorting to analyze a detailed immune profile of tumour samples from HNSCC patients with respect to their HPV status.
Thu Jan 01 00:00:00 UTC 2015
Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance.
The Journal of allergy and clinical immunology
Menard L,Cantaert T,Chamberlain N,Tangye SG,Riminton S,Church JA,Klion A,Cunningham-Rundles C,Nichols KE,Meffre E
53-4776 was used in Flow cytometry/Cell sorting to show SLAM-associated protein expression is necessary for the counterselection of developing autoreactive B cells and prevents their T cell-dependent accumulation in the periphery.
Tue Apr 01 00:00:00 UTC 2014
Tumor-infiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer.
Breast cancer research : BCR
García-Martínez E,Gil GL,Benito AC,González-Billalabeitia E,Conesa MA,García García T,García-Garre E,Vicente V,Ayala de la Peña F
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Sat Nov 29 00:00:00 UTC 2014
Highly heterogeneous, activated, and short-lived regulatory T cells during chronic filarial infection.
European journal of immunology
Metenou S,Coulibaly YI,Sturdevant D,Dolo H,Diallo AA,Soumaoro L,Coulibaly ME,Kanakabandi K,Porcella SF,Klion AD,Nutman TB
53-4776 was used in Flow cytometry/Cell sorting to study how in filarial infection, the expanded Treg-cell populations are heterogeneous, short-lived, activated, and express higher levels of molecules known to modulate immune responsiveness.
Tue Jul 01 00:00:00 UTC 2014
Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells.
Blood
Kinnunen T,Chamberlain N,Morbach H,Choi J,Kim S,Craft J,Mayer L,Cancrini C,Passerini L,Bacchetta R,Ochs HD,Torgerson TR,Meffre E
53-4776 was used in Flow cytometry/Cell sorting to investigate the role of regulatory T cells in maintaining human B-cell tolerance.
Thu Feb 28 00:00:00 UTC 2013
Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.
The Journal of clinical investigation
Mueller C,Chulay JD,Trapnell BC,Humphries M,Carey B,Sandhaus RA,McElvaney NG,Messina L,Tang Q,Rouhani FN,Campbell-Thompson M,Fu AD,Yachnis A,Knop DR,Ye GJ,Brantly M,Calcedo R,Somanathan S,Richman LP,Vonderheide RH,Hulme MA,Brusko TM,Wilson JM,Flotte TR
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunofluorescence
Sun Dec 01 00:00:00 UTC 2013
Specific peripheral B cell tolerance defects in patients with multiple sclerosis.
The Journal of clinical investigation
Kinnunen T,Chamberlain N,Morbach H,Cantaert T,Lynch M,Preston-Hurlburt P,Herold KC,Hafler DA,O'Connor KC,Meffre E
53-4776 was used in Flow cytometry/Cell sorting to demonstrate in multiple sclerosis patients, bone marrow B cell selection is normal, while suffering from peripheral B cell tolerance defects.
Sat Jun 01 00:00:00 UTC 2013
CVID-associated TACI mutations affect autoreactive B cell selection and activation.
The Journal of clinical investigation
Romberg N,Chamberlain N,Saadoun D,Gentile M,Kinnunen T,Ng YS,Virdee M,Menard L,Cantaert T,Morbach H,Rachid R,Martinez-Pomar N,Matamoros N,Geha R,Grimbacher B,Cerutti A,Cunningham-Rundles C,Meffre E
53-4776 was used in Flow cytometry/Cell sorting to demonstrate that TACI mutations may favor common variable immune deficiency by altering B cell activation.
Tue Oct 01 00:00:00 UTC 2013
T regulatory cells and related immunoregulatory factors in polymorphic light eruption following ultraviolet A1 challenge.
The British journal of dermatology
Gambichler T,Terras S,Kampilafkos P,Kreuter A,Skrygan M
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunofluorescence
Sun Dec 01 00:00:00 UTC 2013
Galectin-9 and IL-21 mediate cross-regulation between Th17 and Treg cells during acute hepatitis C.
PLoS pathogens
Kared H,Fabre T,Bédard N,Bruneau J,Shoukry NH
53-4776 was used in Flow cytometry/Cell sorting to longitudinally analyse CD4 helper T cell function as well as the interaction between CD4 and CD8 T cells during acute HCV infection in individuals with spontaneous resolution vs persistent viremia.
Fri Jan 17 00:00:00 UTC 2014
Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).
Arthritis research & therapy
Abdulahad WH,Lepse N,Stegeman CA,Huitema MG,Doornbos-van der Meer B,Tadema H,Rutgers A,Limburg PC,Kallenberg CG,Heeringa P
53-4776 was used in Flow cytometry/Cell sorting to explore a possible role for IL-21 producing Th-cells in the immunopathogenesis of granulomatosis with polyangiitis.
Fri Nov 14 00:00:00 UTC 2014
Human T cells upregulate CD69 after coculture with xenogeneic genetically-modified pig mesenchymal stromal cells.
Cellular immunology
Li J,Andreyev O,Chen M,Marco M,Iwase H,Long C,Ayares D,Shen Z,Cooper DK,Ezzelarab MB
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Jan 20 00:00:00 UTC 2014
Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction.
PloS one
Liu X,Gao N,Li M,Xu D,Hou Y,Wang Q,Zhang G,Sun Q,Zhang H,Zeng X
53-4776 was used in Flow cytometry/Cell sorting to investigate the role of Treg subsets in the immune imbalance in naive systemic sclerosis (SSc), showing that elevated levels of CD4(+)CD25(+)FoxP3(+) T cells contribute to the secretion of IL-17 and immunosuppression dysfunction.
Thu Jan 16 00:00:00 UTC 2014
Induction of endometriosis alters the peripheral and endometrial regulatory T cell population in the non-human primate.
Human reproduction (Oxford, England)
Braundmeier A,Jackson K,Hastings J,Koehler J,Nowak R,Fazleabas A
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Fri Jun 01 00:00:00 UTC 2012
Impaired function of regulatory T cells in cord blood of children of allergic mothers.
Clinical and experimental immunology
Hrdý J,Kocourková I,Prokešová L
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Oct 01 00:00:00 UTC 2012
The vaccine-site microenvironment induced by injection of incomplete Freund's adjuvant, with or without melanoma peptides.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Harris RC,Chianese-Bullock KA,Petroni GR,Schaefer JT,Brill LB,Molhoek KR,Deacon DH,Patterson JW,Slingluff CL
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Sun Jan 01 00:00:00 UTC 2012
OMIP-006: phenotypic subset analysis of human T regulatory cells via polychromatic flow cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Murdoch DM,Staats JS,Weinhold KJ
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Sun Apr 01 00:00:00 UTC 2012
Increased expression of regulatory T cells and down-regulatory molecules in lepromatous leprosy.
The American journal of tropical medicine and hygiene
Palermo ML,Pagliari C,Trindade MA,Yamashitafuji TM,Duarte AJ,Cacere CR,Benard G
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunohistochemistry
Tue May 01 00:00:00 UTC 2012
Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes.
Diabetes
Hughson A,Bromberg I,Johnson B,Quataert S,Jospe N,Fowell DJ
53-4776 was used in Flow cytometry/Cell sorting to determine the relative proportions of effector and regulatory T cells in the CD4+CD25+Foxp3+ T-cell compartment in varying type 1 diabetes disease states.
Mon Aug 01 00:00:00 UTC 2011
Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.
Investigative ophthalmology & visual science
Dasgupta G,Chentoufi AA,You S,Falatoonzadeh P,Urbano LA,Akhtarmalik A,Nguyen K,Ablabutyan L,Nesburn AB,BenMohamed L
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Tue May 17 00:00:00 UTC 2011
CD4(+) regulatory T cells in a cynomolgus macaque model of Mycobacterium tuberculosis infection.
The Journal of infectious diseases
Green AM,Mattila JT,Bigbee CL,Bongers KS,Lin PL,Flynn JL
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Immunofluorescence
Sun Aug 15 00:00:00 UTC 2010
CD40 signalling induces IL-10-producing, tolerogenic dendritic cells.
Experimental dermatology
Tuettenberg A,Fondel S,Steinbrink K,Enk AH,Jonuleit H
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2010
Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis.
PloS one
Smolders J,Peelen E,Thewissen M,Cohen Tervaert JW,Menheere P,Hupperts R,Damoiseaux J
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Dec 13 00:00:00 UTC 2010
A tonsillar PolyICLC/AT-2 SIV therapeutic vaccine maintains low viremia following antiretroviral therapy cessation.
PloS one
Vagenas P,Aravantinou M,Williams VG,Jasny E,Piatak M,Lifson JD,Salazar AM,Blanchard JL,Gettie A,Robbiani M
53-4776 was used in Flow cytometry/Cell sorting to study the efficacy of a mucosally-delivered vaccine in a non-human primate HIV model.
Tue Sep 21 00:00:00 UTC 2010
Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures.
Journal of translational medicine
Bonanno G,Iudicone P,Mariotti A,Procoli A,Pandolfi A,Fioravanti D,Corallo M,Perillo A,Scambia G,Pierelli L,Rutella S
53-4776 was used in Flow cytometry/Cell sorting to investigate whether thymoglobulin can improve the generation efficiency of cytokine-induced killer cells compared with αCD3 monoclonal antibody in a clinical-grade culture protocol.
Tue Dec 07 00:00:00 UTC 2010
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.
Cancer research
François V,Ottaviani S,Renkvist N,Stockis J,Schuler G,Thielemans K,Colau D,Marchand M,Boon T,Lucas S,van der Bruggen P
53-4776 was used in Immunocytochemistry to investigate the CD4+ T-cell response of melanoma patients to a MAGE-A3 peptide vaccine.
Fri May 15 00:00:00 UTC 2009
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.
Cancer research
François V,Ottaviani S,Renkvist N,Stockis J,Schuler G,Thielemans K,Colau D,Marchand M,Boon T,Lucas S,van der Bruggen P
53-4776 was used in Immunocytochemistry to investigate the CD4+ T-cell response of melanoma patients to a MAGE-A3 peptide vaccine.
Fri May 15 00:00:00 UTC 2009
Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Nagata S,Ise T,Pastan I
Published figure using FOXP3 monoclonal antibody (Product # 53-4776-42) in Flow Cytometry
Mon Jun 15 00:00:00 UTC 2009
The importance of Foxp3 antibody and fixation/permeabilization buffer combinations in identifying CD4+CD25+Foxp3+ regulatory T cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Law JP,Hirschkorn DF,Owen RE,Biswas HH,Norris PJ,Lanteri MC
53-4776 was used in Flow cytometry/Cell sorting to develop a multiparameter flow cytometric panel with Foxp3 for optimal identification of Tregs.
Tue Dec 01 00:00:00 UTC 2009
HIV-specific regulatory T cells are associated with higher CD4 cell counts in primary infection.
AIDS (London, England)
Kared H,Lelièvre JD,Donkova-Petrini V,Aouba A,Melica G,Balbo M,Weiss L,Lévy Y
53-4776 was used in Flow cytometry/Cell sorting to show a positive correlation between Treg and CD4 cell counts and magnitude of HIV p24-specific suppressive activity at diagnosis of primary HIV infection.
Sun Nov 30 00:00:00 UTC 2008
IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients.
Blood
Ahmadzadeh M,Rosenberg SA
Wed Mar 15 00:00:00 UTC 2006
Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART.
Blood
Epple HJ,Loddenkemper C,Kunkel D,Tröger H,Maul J,Moos V,Berg E,Ullrich R,Schulzke JD,Stein H,Duchmann R,Zeitz M,Schneider T
Wed Nov 01 00:00:00 UTC 2006
Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Lim HW,Hillsamer P,Banham AH,Kim CH
Sat Oct 01 00:00:00 UTC 2005
