Invitrogen

FOXP3 Monoclonal Antibody (eBio7979 (221D/D3)), eBioscience™

FIGURE: 1 / 12

FOXP3 Antibody (14-7979-82) in WB

Immunoblotting of PBMC (Lane A), BALB/c splenocyte (Lane B), or recombinant human Foxp3 fusion protein (Lane C). Lysates were directly sonicated in Laemmli sample buffer and 10e6 cells/lane were loaded. Blots were probed with 1 µg/mL Anti-Human/Mouse Foxp3 Purified and revealed with Anti-Mouse IgG HRP. Foxp3 is detected at ~50 kDa with a reported splice variant in human tissue slightly lower.

FOXP3 Antibody in Immunocytochemistry (ICC/IF)

FOXP3 Antibody in Immunocytochemistry, Proximity Ligation Assay (PLA) (ICC/IF, PLA)

FOXP3 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

FOXP3 Antibody — Figure 6 Foxp3-positive cells in the thymus. Representative images for Foxp3 expression in the thymus are shown for controls ( A ), 14 d LPS ( B ), and 14 d LPS+7 d Beta group ( C ). D: The percentage of Foxp3-positive stained area in the thymic medulla decreased in the animals exposed to 14 days of LPS independent of Beta treatment. Magnification 200x; magnification insert: 400x. * p<0.05 versus controls. {TM}

Product Details

14-7979-82

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 16 publications 16 publications

Immunohistochemistry (IHC)

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 5 publications 5 publications

Immunohistochemistry (Frozen) (IHC (F))

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

ChIP assay (ChIP)

View 1 publication 1 publication

in situ PLA (PLA)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Dog, Human, Mouse, Sheep

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

eBio7979 (221D/D3)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_468500

Product Specific Information

Description: eBioscience offers a panel of monoclonal antibodies to different epitopes of human and mouse Foxp3, providing useful tools for investigating the complete expression pattern of Foxp3 at the protein level, and discerning the precise subsets of Foxp3+ cells. Other antibodies to human Foxp3 include PCH101 (Product # 72-5776) and 236A/E7 (Product # 12-4777) . Additional antibodies to mouse Foxp3 include FJK-16s (Product # 72-5775) and NRRF-30 (Product # 12-4771) .

The eBio7979 antibody reacts with human and mouse foxp3 protein also known as FORKHEAD BOX P3, SCURFIN, and JM2; cross reactivity of this antibody to other proteins has not been determined. Foxp3, a 49-55 kDa protein, is a member of the forkhead/winged-helix family of transcriptional regulators, and was identified as the gene defective in 'scurfy' (sf) mice. Constitutive high expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg cells), and ectopic expression of foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.

Please see our FAQ regarding the usage of eBioscience Foxp3 reagents.

Applications Reported: This eBio7979 antibody has been reported for use in immunoblotting (WB).

Applications Tested: This eBio7979 antibody has been tested by immunoblotting of normal human peripheral blood mononuclear cell lysates at 1-2 µg/mL.

Purity: Greater than 90%, as determined by SDS-PAGE.

Aggregation: Less than 10%, as determined by HPLC.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome. Transcript variants of FOXP3 encoding different isoforms have been identified. In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

hnRNPA1 enhances FOXP3 stability to promote the differentiation and functions of regulatory T cells.

FEBS letters

Liu X,Tian N,Huang Q,Xu Z,Cheng H,Liu X,Li D,Liang R,Li B,Dai X

14-7979-82 was used in Flow cytometry/Cell sorting to present a new role of hnRNPA1 in promoting Treg function, indicating it as a promising target for tumor therapies.

Thu Jul 01 00:00:00 UTC 2021

Expression of FOXP3 in Canine Gliomas: Immunohistochemical Study of Tumor-Infiltrating Regulatory Lymphocytes.

Journal of neuropathology and experimental neurology

Pi Castro D,José-López R,Fernández Flores F,Rabanal Prados RM,Mandara MT,Arús C,Pumarola Batlle M

14-7979 was used in Immunohistochemistry to immunohistochemically characterize the tumor-infiltrating lymphocyte (TIL) population of naturally occurring canine gliomas, focusing on the expression of Forkhead box P3-positive (FOXP3+) regulatory T-cells (Tregs).

Sat Feb 01 00:00:00 UTC 2020

Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function.

Frontiers in immunology

Wang A,Yang M,Liang R,Zhu F,Zhu F,Liu X,Han Y,Lin R,Wang X,Li D,Li H,Yuan X,Zhao H,Li B

14-7979 was used in Western Blotting to investigate how mouse double minute 2 homolog effects the function of regulatory T cells.

Mon Apr 05 00:00:00 UTC 2021

Changes in Expression of Multiple Checkpoint Molecules and Infiltration of Tumor Immune Cells after Neoadjuvant Chemotherapy in Gastric Cancer.

Journal of Cancer

Yu Y,Ma X,Zhang Y,Zhang Y,Ying J,Zhang W,Zhong Q,Zhou A,Zeng Y

14-7979-82 was used in Immunohistochemistry to characterize the changes in tumor-infiltrating immune cells and checkpoint molecules following NACT and investigate the prognostic value of these changes in LAGC.

Thu Oct 01 00:00:00 UTC 2020

Changes in Expression of Multiple Checkpoint Molecules and Infiltration of Tumor Immune Cells after Neoadjuvant Chemotherapy in Gastric Cancer.

Journal of Cancer

Yu Y,Ma X,Zhang Y,Zhang Y,Ying J,Zhang W,Zhong Q,Zhou A,Zeng Y

Thu Oct 01 00:00:00 UTC 2020

Silencing of CD86 in dendritic cells by small interfering RNA regulates cytokine production in T cells from patients with allergic rhinitis in vitro.

Molecular medicine reports

Sun R,Yang Y,Gu Z,Tang X,Zhang C,Kou W,Wei P

14-7979 was used in Western Blotting to present a study indicating that CD86 may play a pivotal role in the regulatory T cell/type 2 helper T cell imbalance in allergic inflammation.

Tue Oct 01 00:00:00 UTC 2019

Off-Target Deletion of Conditional Dbc1 Allele in the Foxp3^YFP-Cre Mouse Line under Specific Setting.

Cells

Xie C,Zhu F,Wang J,Zhang W,Bellanti JA,Li B,Brand D,Olsen N,Zheng SG

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Western Blot

Thu Oct 24 00:00:00 UTC 2019

Aneustat (OMN54) has aerobic glycolysis-inhibitory activity and also immunomodulatory activity as indicated by a first-generation PDX prostate cancer model.

International journal of cancer

Qu S,Xue H,Dong X,Lin D,Wu R,Nabavi N,Collins CC,Gleave ME,Gout PW,Wang Y

14-7979 was used in Immunohistochemistry on paraffin embedded tissues to indicate that Aneustat has immunomodulatory activity based on inhibition of aerobic glycolysis which in patients may reduce cancer-induced immunosuppression.

Sun Jul 15 00:00:00 UTC 2018

Ring finger protein 31-mediated atypical ubiquitination stabilizes forkhead box P3 and thereby stimulates regulatory T-cell function.

The Journal of biological chemistry

Zhu F,Yi G,Liu X,Zhu F,Zhao A,Wang A,Zhu R,Chen Z,Zhao B,Fang S,Yu X,Lin R,Liang R,Li D,Zhao W,Zhang Z,Guo W,Zhang S,Ge S,Fan X,Zhao G,Li B

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Immunocytochemistry

Fri Dec 28 00:00:00 UTC 2018

Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3.

BMC biology

Schmidt A,Marabita F,Kiani NA,Gross CC,Johansson HJ,Éliás S,Rautio S,Eriksson M,Fernandes SJ,Silberberg G,Ullah U,Bhatia U,Lähdesmäki H,Lehtiö J,Gomez-Cabrero D,Wiendl H,Lahesmaa R,Tegnér J

Mon May 07 00:00:00 UTC 2018

Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells.

Methods in molecular biology (Clifton, N.J.)

Jiao J,Han R,Hancock WW,Beier UH

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Immunocytochemistry

Tue Jan 09 00:00:00 UTC 2018

Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells.

Methods in molecular biology (Clifton, N.J.)

Jiao J,Han R,Hancock WW,Beier UH

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Immunocytochemistry

Tue Jan 09 00:00:00 UTC 2018

Hypercholesterolemia Enhances T Cell Receptor Signaling and Increases the Regulatory T Cell Population.

Scientific reports

Mailer RKW,Gisterå A,Polyzos KA,Ketelhuth DFJ,Hansson GK

14-7979 was used in Western Blotting to investigate the phenotype and function of T cell subpopulations in hypercholesterolaemia.

Wed Nov 15 00:00:00 UTC 2017

Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation.

Oncotarget

Jou YC,Tsai YS,Lin CT,Tung CL,Shen CH,Tsai HT,Yang WH,Chang HI,Chen SY,Tzai TS

14797982 was used in western blot to show reverse post-translational regulation of HIF-1alpha by Foxp3

Tue Oct 04 00:00:00 UTC 2016

Altered connexin 43 expression underlies age-dependent decrease of regulatory T cell suppressor function in nonobese diabetic mice.

Journal of immunology (Baltimore, Md. : 1950)

Kuczma M,Wang CY,Ignatowicz L,Gourdie R,Kraj P

14-7979 was used in Western Blotting to identify gap junction-mediated intercellular communication as an important component of the T(reg) suppression mechanism compromised in nonobese diabetic mice.

Mon Jun 01 00:00:00 UTC 2015

Responses of the spleen to intraamniotic lipopolysaccharide exposure in fetal sheep.

Pediatric research

Kuypers E,Willems MG,Jellema RK,Kemp MW,Newnham JP,Delhaas T,Kallapur SG,Jobe AH,Wolfs TG,Kramer BW

14-7979 was used in Immunohistochemistry on paraffin embedded tissues to study how the foetal spleen responds to intrauterine inflammation over time.

Thu Jan 01 00:00:00 UTC 2015

An acute intake of plant stanol esters alters immune-related pathways in the jejunum of healthy volunteers.

The British journal of nutrition

De Smet E,Mensink RP,Boekschoten MV,de Ridder R,Germeraad WT,Wolfs TG,Plat J

14-7979-82 was used in Immunohistochemistry (Frozen) to examine the effects of an acute intake of plant stanol esters on gene expression profiles of the upper small intestine in healthy volunteers.

Sat Mar 14 00:00:00 UTC 2015

CD4+ T lymphocyte ablation prevents pancreatic carcinogenesis in mice.

Cancer immunology research

Zhang Y,Yan W,Mathew E,Bednar F,Wan S,Collins MA,Evans RA,Welling TH,Vonderheide RH,di Magliano MP

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Immunohistochemistry

Thu May 01 00:00:00 UTC 2014

Chorioamnionitis-induced fetal gut injury is mediated by direct gut exposure of inflammatory mediators or by lung inflammation.

American journal of physiology. Gastrointestinal and liver physiology

Wolfs TG,Kramer BW,Thuijls G,Kemp MW,Saito M,Willems MG,Senthamarai-Kannan P,Newnham JP,Jobe AH,Kallapur SG

14-7979 was used in Immunohistochemistry to show that both local gut and lung-mediated inflammatory responses are causative of chorioamnionitis in the fetal gut.

Sat Mar 01 00:00:00 UTC 2014

Intraamniotic lipopolysaccharide exposure changes cell populations and structure of the ovine fetal thymus.

Reproductive sciences (Thousand Oaks, Calif.)

Kuypers E,Wolfs TG,Collins JJ,Jellema RK,Newnham JP,Kemp MW,Kallapur SG,Jobe AH,Kramer BW

14-7979 was used in Immunohistochemistry on paraffin embedded tissues to study the immune response, cell composition and architecture of the foetal thymus following intra-amniotic lipopolysaccharide exposure.

Thu Aug 01 00:00:00 UTC 2013

Selective exposure of the fetal lung and skin/amnion (but not gastro-intestinal tract) to LPS elicits acute systemic inflammation in fetal sheep.

PloS one

Kemp MW,Kannan PS,Saito M,Newnham JP,Cox T,Jobe AH,Kramer BW,Kallapur SG

14-7979 was used in Immunohistochemistry to reveal differential fetal organ responses to pro-inflammatory stimulation and shed light on the pathogenesis of fetal systemic inflammation after exposure to chorioamnionitis.

Mon Dec 16 00:00:00 UTC 2013

Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma.

PloS one

Townsend KN,Spowart JE,Huwait H,Eshragh S,West NR,Elrick MA,Kalloger SE,Anglesio M,Watson PH,Huntsman DG,Lum JJ

14-7979 was used in Immunohistochemistry to determine whether tumour vasculature influences the functional capacity of tumour infiltrating lymphocytes, and correlate this with survival in ovarian cancer patients.

Tue Mar 03 00:00:00 UTC 2015

Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs.

American journal of physiology. Lung cellular and molecular physiology

Kuypers E,Collins JJ,Kramer BW,Ofman G,Nitsos I,Pillow JJ,Polglase GR,Kemp MW,Newnham JP,Gavilanes AW,Nowacki R,Ikegami M,Jobe AH,Kallapur SG

14-7979 was used in Immunohistochemistry to investigate how the order of exposures of intra-amniotic LPS or maternal betamethasone has large effects on fetal lung inflammation and maturation.

Wed Feb 15 00:00:00 UTC 2012

Ovine fetal thymus response to lipopolysaccharide-induced chorioamnionitis and antenatal corticosteroids.

PloS one

Kuypers E,Collins JJ,Jellema RK,Wolfs TG,Kemp MW,Nitsos I,Pillow JJ,Polglase GR,Newnham JP,Germeraad WT,Kallapur SG,Jobe AH,Kramer BW

14-7979 was used in Immunohistochemistry-immunofluorescence to test the hypothesis that intra-amniotic exposure to lipopolysaccharide causes involution of the foetal thymus resulting in persistent effects on thymic structure and cell populations.

Mon Oct 22 00:00:00 UTC 2012

Ovine fetal thymus response to lipopolysaccharide-induced chorioamnionitis and antenatal corticosteroids.

PloS one

Kuypers E,Collins JJ,Jellema RK,Wolfs TG,Kemp MW,Nitsos I,Pillow JJ,Polglase GR,Newnham JP,Germeraad WT,Kallapur SG,Jobe AH,Kramer BW

Mon Oct 22 00:00:00 UTC 2012

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation.

Nature immunology

Beyer M,Thabet Y,Müller RU,Sadlon T,Classen S,Lahl K,Basu S,Zhou X,Bailey-Bucktrout SL,Krebs W,Schönfeld EA,Böttcher J,Golovina T,Mayer CT,Hofmann A,Sommer D,Debey-Pascher S,Endl E,Limmer A,Hippen KL,Blazar BR,Balderas R,Quast T,Waha A,Mayer G,Famulok M,Knolle PA,Wickenhauser C,Kolanus W,Schermer B,Bluestone JA,Barry SC,Sparwasser T,Riley JL,Schultze JL

14-7979 was used in Immunofluorescence to show that SATB1 control by Foxp3 is an essential and critical mechanism maintaining Treg cell functionality.

Sun Aug 14 00:00:00 UTC 2011

FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1.

Molecular cell

Katoh H,Qin ZS,Liu R,Wang L,Li W,Li X,Wu L,Du Z,Lyons R,Liu CG,Liu X,Dou Y,Zheng P,Liu Y

14-7979 was used in Chromatin immunoprecipitation to demonstrate the involvement of FOXP3 in catalyzing the epigenetic modifications, H4K16 acetylation and H3K4 trimethylation.

Fri Dec 09 00:00:00 UTC 2011

Pulmonary and systemic inflammatory responses to intra-amniotic IL-1α in fetal sheep.

American journal of physiology. Lung cellular and molecular physiology

Kallapur SG,Kramer BW,Nitsos I,Pillow JJ,Collins JJ,Polglase GR,Newnham JP,Jobe AH

14-7979 was used in Immunohistochemistry on paraffin embedded tissues to determine downstream organ-specific effects of intra-amniotic IL-1α on inflammatory responses in preterm fetal sheep, with an emphasis on the lung.

Thu Sep 01 00:00:00 UTC 2011

Connexin 43 signaling enhances the generation of Foxp3+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950)

Kuczma M,Lee JR,Kraj P

14-7979 was used in Western Blotting to identify a novel signaling pathway, controlled by Cx43, that enhances the generation of T(R) cells.

Fri Jul 01 00:00:00 UTC 2011

Neonatal bacillus Calmette-Guérin vaccination inhibits de novo allergic inflammatory response in mice via alteration of CD4+CD25+ T-regulatory cells.

Acta pharmacologica Sinica

Li Q,Shen HH

14-7979 was used in Western Blotting to show that neonatal BCG vaccinations ameliorate de novo local eosinophilic inflammation induced by allergen and increase the numbers of CD4+CD25+ Treg cells and Foxp3 expression.

Thu Jan 01 00:00:00 UTC 2009

TCR repertoire and Foxp3 expression define functionally distinct subsets of CD4+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950)

Kuczma M,Pawlikowska I,Kopij M,Podolsky R,Rempala GA,Kraj P

14-7979 was used in Western Blotting to investigate how T(reg) cells expressing TCRs shared with naive CD4(+) T cells have a flexible phenotype and may down-regulate Foxp3 expression.

Tue Sep 01 00:00:00 UTC 2009

Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950)

Ellestad KK,Tsutsui S,Noorbakhsh F,Warren KG,Yong VW,Pittman QJ,Power C

14-7979 was used in Western Blotting to support the concept of early-life microbial exposure influencing the generation of neuroprotective regulatory T cells in relation to autoimmune diseases.

Wed Jul 01 00:00:00 UTC 2009

IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis.

PloS one

Mas E,Danjoux M,Garcia V,Carpentier S,Ségui B,Levade T

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Western Blot

Fri Nov 20 00:00:00 UTC 2009

Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells.

Blood

Samon JB,Champhekar A,Minter LM,Telfer JC,Miele L,Fauq A,Das P,Golde TE,Osborne BA

14-7979 was used in Western Blotting to determine the effects of pharmacologic inhibition of Notch signalling using gamma-secretase inhibitor, on Foxp3 expression and regulatory T-cell maintenance.

Mon Sep 01 00:00:00 UTC 2008

IL-15 acts as a potent inducer of CD4(+)CD25(hi) cells expressing FOXP3.

European journal of immunology

Imamichi H,Sereti I,Lane HC

14-7979 was used in Western Blotting to study the effects of IL-15 on the induction of CD25 expression on CD4+ T cells, FOXP3 expression, and suppressor cell activity.

Sun Jun 01 00:00:00 UTC 2008

Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer.

PloS one

Milne K,Barnes RO,Girardin A,Mawer MA,Nesslinger NJ,Ng A,Nielsen JS,Sahota R,Tran E,Webb JR,Wong MQ,Wick DA,Wray A,McMurtrie E,Köbel M,Kalloger SE,Gilks CB,Watson PH,Nelson BH

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Immunohistochemistry

Thu Dec 18 00:00:00 UTC 2008

Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation.

The Journal of biological chemistry

Chen C,Rowell EA,Thomas RM,Hancock WW,Wells AD

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Western Blot

Fri Dec 01 00:00:00 UTC 2006

Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation.

The Journal of biological chemistry

Chen C,Rowell EA,Thomas RM,Hancock WW,Wells AD

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Western Blot

Fri Dec 01 00:00:00 UTC 2006

Transcriptional regulation by Foxp3 is associated with direct promoter occupancy and modulation of histone acetylation.

The Journal of biological chemistry

Chen C,Rowell EA,Thomas RM,Hancock WW,Wells AD

Published figure using FOXP3 monoclonal antibody (Product # 14-7979-82) in Western Blot

Fri Dec 01 00:00:00 UTC 2006

Bioinformatics

Protein Aliases: Forkhead box protein P3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; MGC141961; MGC141963; RP23-54C14.1; Scurfin; scurfy

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Gene Aliases: AIID; DIETER; FOXP3; IPEX; JM2; PIDX; scurfin; sf; XPID

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UniProt ID: (Human) Q9BZS1, (Mouse) Q99JB6

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Entrez Gene ID: (Human) 50943, (Mouse) 20371

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Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription corepressor activity protein binding histone acetyltransferase binding protein homodimerization activity histone deacetylase binding sequence-specific DNA binding metal ion binding NF-kappaB binding NFAT protein binding nucleic acid binding DNA binding

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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FOXP3 Monoclonal Antibody (eBio7979 (221D/D3)), eBioscience™

FOXP3 Antibody (14-7979-82) in WB

Product Details

14-7979-82

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (Frozen) (IHC (F))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

in situ PLA (PLA)

Species Reactivity

Published species

Host/Isotype

Class

Type

Clone

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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