Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
24937-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FPGT Fusion Protein Ag20655 (1-354 aa encoded by BC032308)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAARDPPE VSLREATQRK LRRFSELRGK LVARGEFWDI VAITAADEKQ ELAYNQQLSE KLKRKELPLG VQYHVFVDPA GAKIGNGGST LCALQCLEKL YGDKWNSFTI LLIHSGGYSQ RLPNASALGK IFTALPLGNP IYQMLELKLA MYIDFPLNMN PGILVTCADD IELYSIGEFE FIRFDKPGFT ALAHPSSLTI GTTHGVFVLD PFDDLKHRDL EYRSCHRFLH KPSIEKMYQF NAVCRPGNFC QQDFAGGDIA DLKLDSDYVY TDSLFYMDHK SAKMLLAFYE KIGTLSCEID AYGDFLQALG PGATVEYTRN TSNVIKEESE LVEMRQRIFH LLKGTSLNVV VLNNS (1-354 aa encoded by BC032308)
Target Information
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: fucose-1-phosphate guanyltransferase; Fucose-1-phosphate guanylyltransferase; GDP-beta-L-fucose pyrophosphorylase; GDP-L-fucose diphosphorylase; GDP-L-fucose pyrophosphorylase
Gene Aliases: 1700016E03Rik; FPGT; GFPP
UniProt ID: (Human) O14772, (Mouse) G5E8F4
Entrez Gene ID: (Human) 8790, (Mouse) 75540
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support