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Proteintech
FREM1 Polyclonal Antibody
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Product Details
13086-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FREM1 Fusion Protein Ag3617 (412-710 aa encoded by BC031064)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognizes isoform 1 (244 kDa), isoform 2 (80 kDa) and isoform 3 (43 kDa).
Immunogen sequence: SSSTTSGSF HLERRPLPSS MQLAVIRGDT LRGFDSTDLS QRKLRTRGNG KTVRPSSVYR NGTDIIYNYH GIVSLKLEDD SFPTHKRKAK VSIISQPQKT IKVAELPQAD KVESTTDSHF PRQDQLPSFP KNCTLELKGL FHFEEGIQKL YQCNGIAWKA WSPQTKDVED KSCPAGWHQH SGYCHILITE QKGTWNAAAQ ACREQYLGNL VTVFSRQHMR WLWDIGGRKS FWIGLNDQVH AGHWEWIGGE PVAFTNGRRG PSPRSKLGKS CVLVQRQGKW QTKDCRRAKP HNYGCSRKL (412-710 aa encoded by BC031064)
Target Information
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: extracellular matrix protein QBRICK; FRAS1-related extracellular matrix protein 1; Protein QBRICK; RP11-265B7.2
Gene Aliases: BNAR; C9orf143; C9orf145; C9orf154; FREM1; MOTA; TILRR; TRIGNO2
UniProt ID: (Human) Q5H8C1
Entrez Gene ID: (Human) 158326
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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