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Abnova
FRZB Polyclonal Antibody, MaxPab™
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Product Details
H00002487-D01P
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FRZB (NP_001454.2, 1 a.a. approximately 325 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVCGSPGGML LLRAGLLALA ALCLLRVPGA RAAACEPVRI PLCKSLPWNM TKMPNHLHHS TQANAILAIE QFEGLLGTHC SPDLLFFLCA MYAPICTIDF QHEPIKPCKS VCERARQGCE PILIKYRHSW PENLACEELP VYDRGVCISP EAIVTADGAD FPMDSSNGNC RGASSERCKC KPIRATQKTY FRNNYNYVIR AKVKEIKTKC HDVTAVVEVK EILKSSLVNI PRDTVNLYTS SGCLCPPLNV NEEYIIMGYE DEERSRLLLV EGSIAEKWKD RLGKKVKRWD MKLRHLGLSK SDSSNSDSTQ SQKSGRNSNP RQARN
Target Information
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FREOS1; Frezzled; Fritz; frizzled homolog-related; Frizzled-related protein 1; FrzB-1; FRZB1sFRP-3; Secreted frizzled-related protein 3; secreted frizzled-related sequence protein 3; sFRP-3; SFRP3frezzled
Gene Aliases: FIZ; FRE; frezzled; FRITZ; FRP; FRP-3; FRZB; FRZB-1; FRZB-PEN; FRZB1; FZRB; hFIZ; OS1; SFRP3; SRFP3
UniProt ID: (Human) Q92765, (Mouse) P97401
Entrez Gene ID: (Human) 2487, (Mouse) 20378, (Rat) 295691
skeletal system development
G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
negative regulation of cell development
neural crest cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
non-canonical Wnt signaling pathway
positive regulation of apoptotic process
positive regulation of fat cell differentiation
convergent extension involved in organogenesis
negative regulation of cartilage development
somite development
negative regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
multicellular organism development
Wnt signaling pathway
cell differentiation
inner ear morphogenesis
canonical Wnt signaling pathway
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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