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Immunogen sequence: SNISEPTKKV MEMIPQISSF CLVRDRNHIQ SANLDEEAQA GTSSLQVMLD HHPVAITVEV KQEEDIKPPP PLVLNSQQSD TLEQREEHEL VHVMERSLSP
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 81%.
Fibrinogen silencer-binding protein, Function: Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1. Subunit structure: Interacts with APBA1 (via PDZ 1 and 2 domains). Subcellular location: Nucleus. Tissue specificity: Expressed in multiple tissues including brain. Miscellaneous: Intragenic, in the second intron of RAB54B gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fibrinogen silencer-binding protein
Gene Aliases: FSBP
UniProt ID: (Human) O95073
Entrez Gene ID: (Human) 100861412
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