Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: QNDAGVRIQF KPDDGTTPER IAQITGPPDR CQHAAEIITD LLRSVQAGNP GGPGPGGRGR GRGQGNWNMG PPGGLQEFNF IVPTGKTGLI IGKGGETIKS ISQQSGARIE LQRNPPPNAD PNMKLFTIRG TPQQIDYARQ LIEEKIGGPV NPLGPPVPHG PHGVPGPHGP PGPPGPGTPM GPYNPAPYNP GPPGPAPHGP PAPYAPQGWG NAYPHWQQQA PPDPAKAGTD PNSAAWAAYY AHYYQQQAQP PPAAPAGAPT TTQTNGQGDQ QNPAPAGQVD YTKAWEEYYK KMGQAVPAPT GAPPGGQPDY SAAWAEYYRQ QAAYYAQTSP QGMPQHPPAP QGQ; Positive Samples: U-87MG, HeLa, HepG2, THP-1, Mouse brain; Cellular Location: Nucleus
This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA helicase V; far upstream element (FUSE) binding protein 1; far upstream element (FUSE) binding protein 4; Far upstream element-binding protein 1; far upstream element-binding protein 1 {ECO:0000250|UniProtKB:Q96AE4, ECO:0000312|EMBL:AAI07943.1}; FBP; FBP {ECO:0000250|UniProtKB:Q96AE4}; fubp1 {ECO:0000312|EMBL:AAI07943.1, ECO:0000312|RGD:1591892}; FUSE binding protein 1; FUSE-binding protein 1; FUSE-binding protein 1 {ECO:0000250|UniProtKB:Q96AE4}; hDH V
Gene Aliases: 9530027K12Rik; D3Ertd330e; FBP; FUBP; FUBP1; Fubp4; hDH V
UniProt ID: (Human) Q96AE4, (Rat) Q32PX7
Entrez Gene ID: (Human) 8880, (Rat) 654496, (Mouse) 51886
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