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Invitrogen
FUCA2 Polyclonal Antibody
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FIGURE: 1 / 3
FUCA2 Antibody (PA5-109741) in IHC (P)
Immunohistochemistry analysis of FUCA2 in paraffin-embedded human liver cancer. Samples were incubated with FUCA2 Polyclonal antibody (Product # PA5-109741) using a dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-109741
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 118-467 of human FUCA2 (NP_114409.2).
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855152
Product Specific Information
Immunogen sequence: ADIFQASGAK YIVLTSKHHE GFTLWGSEYS WNWNAIDEGP KRDIVKELEV AIRNRTDLRF GLYYSLFEWF HPLFLEDESS SFHKRQFPVS KTLPELYELV NNYQPEVLWS DGDGGAPDQY WNSTGFLAWL YNESPVRGTV VTNDRWGAGS ICKHGGFYTC SDRYNPGHLL PHKWENCMTI DKLSWGYRRE AGISDYLTIE ELVKQLVETV SCGGNLLMNI GPTLDGTISV VFEERLRQMG SWLKVNGEAI YETHTWRSQN DTVTPDVWYT SKPKEKLVYA IFLKWPTSGQ LFLGHPKAIL GATEVKLLGH GQPLNWISLE QNGIMVELPQ LTIHQMPCKW GWALALTNVI
Target Information
FUCA2 (Alpha-L-fucosidase) catalyzes the hydrolysis of terminal alpha-L-fucosidase linkages in glycosphingolipids and glycoproteins. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man. The FUCA2 locus regulates the level of alpha-fucosidase in plasma and fibroblasts but not in leukocytes. In fucosidosis, deficiency of alpha-L-fucosidase is found in both plasma and leukocytes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-L-fucosidase 2; Alpha-L-fucoside fucohydrolase 2; MGC1314; Plasma alpha-L-fucosidase
Gene Aliases: 0610025O11Rik; 5530401P20Rik; dJ20N2.5; FUCA2; PSEC0151; UNQ227/PRO260
UniProt ID: (Human) Q9BTY2, (Mouse) Q99KR8, (Rat) Q6AYS4
Entrez Gene ID: (Human) 2519, (Mouse) 66848, (Rat) 292485
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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