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          • Primary Antibodies ›
          • FXR1 Antibodies

          Invitrogen

          FXR1 Polyclonal Antibody

          View all (18) FXR1 antibodies

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          Datasheet
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          Datasheet
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          Cite FXR1 Polyclonal Antibody

          • Antibody Testing Data (4)
          FXR1 Antibody in Immunocytochemistry (ICC/IF)
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          FXR1 Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 4

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          FXR1 Antibody (PA5-29853) in ICC/IF

          Immunocytochemistry analysis of FXR1 in methanol-fixed HeLa. Samples were incubated with FXR1 polyclonal antibody (Product # PA5-29853) using a dilution of 1:100. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FXR1 Antibody in Immunocytochemistry (ICC/IF)
          FXR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          FXR1 Antibody in Western Blot (WB)
          FXR1 Antibody in Western Blot (WB)

          Product Details

          PA5-29853

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:1,000
          -

          Immunoprecipitation (IP)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human FXR1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.03 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 20% glycerol

          Contains

          0.025% ProClin 300

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2547327

          Product Specific Information

          Recommended positive controls: HeLa, HepG2, mouse liver.

          Predicted reactivity: Mouse (99%), Rat (89%), Zebrafish (82%), Xenopus laevis (91%), Chicken (86%), Bovine (99%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FMR1 autosomal homolog 1; fragile X mental retardation autosomal homolog variant p1K; fragile X mental retardation autosomal homolog variant p2K; fragile X mental retardation autosomal homolog variant p4K; fragile X mental retardation autosomal homolog variant p5FK; fragile X mental retardation gene, autosomal homolog; fragile X mental retardation syndrome-related protein 1; fragile X mental retardation, autosomal homolog 1; fragile X mental retardation-related protein 1; fragile-X-related protein 1; FXR1P; hFXR1p; mFxr1p; RNA-binding protein FXR1

          View more View less

          Gene Aliases: 1110050J02Rik; 9530073J07Rik; AI851072; FXR1; Fxr1h; FXR1P

          View more View less

          UniProt ID: (Human) P51114, (Rat) Q5XI81, (Mouse) Q61584

          View more View less

          Entrez Gene ID: (Human) 8087, (Rat) 361927, (Mouse) 14359

          View more View less

          Function(s)
          G-quadruplex RNA binding RNA binding mRNA binding mRNA 3'-UTR binding protein binding RNA strand annealing activity protein homodimerization activity poly(A) RNA binding protein heterodimerization activity nucleic acid binding
          Process(es)
          apoptotic process muscle organ development negative regulation of translation cell differentiation positive regulation of gene silencing by miRNA multicellular organism development
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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